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  • BRCA1 Testing in Families With Hereditary Breast-Ovarian Cancer: A Prospective Study of Patient Decision Making and Outcomes

    Abstract Full Text
    JAMA. 1996; 275(24):1885-1892. doi: 10.1001/jama.1996.03530480027036
  • Testing for BRCA1 in Hereditary Breast Cancer

    Abstract Full Text
    JAMA. 1995; 273(11):845-846. doi: 10.1001/jama.1995.03520350027019
  • Testing for BRCA1 in Hereditary Breast Cancer-Reply

    Abstract Full Text
    JAMA. 1995; 273(11):846-846. doi: 10.1001/jama.1995.03520350027020
  • Survival in Hereditary Breast and Colon Cancer

    Abstract Full Text
    JAMA. 1981; 246(11):1197-1197. doi: 10.1001/jama.1981.03320110013015
  • Salpingo-oophorectomy and the Risk of Ovarian, Fallopian Tube, and Peritoneal Cancers in Women With a BRCA1 or BRCA2 Mutation

    Abstract Full Text
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    JAMA. 2006; 296(2):185-192. doi: 10.1001/jama.296.2.185
  • Founder and Recurrent CDH1 Mutations in Families With Hereditary Diffuse Gastric Cancer

    Abstract Full Text
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    JAMA. 2007; 297(21):2360-2372. doi: 10.1001/jama.297.21.2360
  • Limited Family Structure and BRCA Gene Mutation Status in Single Cases of Breast Cancer

    Abstract Full Text
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    JAMA. 2007; 297(23):2587-2595. doi: 10.1001/jama.297.23.2587
  • Genetic Testing of Families With Hereditary Diseases

    Abstract Full Text
    JAMA. 1996; 276(14):1138-1139. doi: 10.1001/jama.1996.03540140026016
  • Genetic Testing of Families With Hereditary Diseases

    Abstract Full Text
    JAMA. 1996; 276(14):1139-1139. doi: 10.1001/jama.1996.03540140027017
  • Clinical Interpretation and Implications of Whole-Genome Sequencing

    Abstract Full Text
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    JAMA. 2014; 311(10):1035-1045. doi: 10.1001/jama.2014.1717

    Dewey and colleagues found that depending on the sequencing platform used, there was incomplete coverage of inherited disease genes, low reproducibility of potentially clinically significant genetic variation, and uncertainty about clinically reportable findings.

  • Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

    Abstract Full Text
    JAMA. 2017; 317(23):2402-2416. doi: 10.1001/jama.2017.7112

    This cohort study estimates age-specific risks of breast, ovarian, and contralateral breast cancer among carriers of BRCA1 and BRCA2 mutations and evaluates risk modification by family cancer history and location of the mutation within the BRCA gene.

  • Effect of Topical Intranasal Therapy on Epistaxis Frequency in Patients With Hereditary Hemorrhagic Telangiectasia: A Randomized Clinical Trial

    Abstract Full Text
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    JAMA. 2016; 316(9):943-951. doi: 10.1001/jama.2016.11724

    This randomized clinical trial assesses whether topical therapy with either bevacizumab, estriol, or tranexamic acid that have differing mechanisms of action is effective in reducing hereditary hemorrhagic telangiectasia–related epistaxis in 121 adult patients treated at 6 US centers of excellence.

  • Breast MRI for Women With Hereditary Cancer Risk

    Abstract Full Text
    JAMA. 2004; 292(11):1368-1370. doi: 10.1001/jama.292.11.1368
  • Mammography Screening in Women Under Age 50 Years

    Abstract Full Text
    JAMA. 1988; 260(4):473-474. doi: 10.1001/jama.1988.03410040045011
  • Association of Type and Location of BRCA1 and BRCA2 Mutations With Risk of Breast and Ovarian Cancer

    Abstract Full Text
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    JAMA. 2015; 313(13):1347-1361. doi: 10.1001/jama.2014.5985

    This genetic epidemiology study reports that risk of breast and ovarian cancer among women with BRCA1 and BRCA2 mutations varies by mutation type and location.

  • Familial Risk and Heritability of Cancer Among Twins in Nordic Countries

    Abstract Full Text
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    JAMA. 2016; 315(1):68-76. doi: 10.1001/jama.2015.17703

    This study estimates familial risk and heritability of cancer types in a large twin cohort using data from population-based registers in Denmark, Finland, Norway, and Sweden.

  • Expertise vs Evidence in Assessment of Breast Biopsies: An Atypical Science

    Abstract Full Text
    JAMA. 2015; 313(11):1109-1110. doi: 10.1001/jama.2015.1945
  • Family Tree Can Yield Lifesaving Knowledge for Patients at Risk for Hereditary Cancers

    Abstract Full Text
    JAMA. 1992; 268(17):2348-2349. doi: 10.1001/jama.1992.03490170012003