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  • Better

    Abstract Full Text
    JAMA. 2017; 318(15):1441-1442. doi: 10.1001/jama.2017.13537
  • Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review

    Abstract Full Text
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    JAMA. 2016; 316(13):1392-1401. doi: 10.1001/jama.2016.14337

    This systematic review summarizes current evidence on effective treatments for nausea and vomiting in pregnancy and hyperemesis gravidarum.

  • JAMA May 10, 2016

    Figure 1: Screening, Randomization, and Follow-up

    aSignificant medical history includes all children with known gastrointestinal diseases (ie, inflammatory bowel disease, celiac disease) or any other underlying disease process that might place the child at an increased risk of treatment failure.bOne child did not receive electrolyte maintenance solution as randomized during the period between randomization and provision of study medications; the family left the emergency department (ED). The family was contacted to enable provision of the supplies but declined to initiate their use at that time.cThese categories are not mutually exclusive.dReasons for absent Canadian Institute for Health Information data: 6 cases with enrollment dates after April 1, 2015 (data unavailable until 2016), 13 with invalid health care numbers, and 12 without any data.eCaregivers were contacted daily to track outcomes (revisits, intravenous fluid administration, and hospitalization). Calls were be made by a research nurse using a standardized set of questions and responses to caregiver queries.fAll participants were provided a diary in which to record follow-up health care clinician visits, diarrhea, vomiting, child care, expenses, and fluids administered. These were returned at the final in-person reassessment or by mail.gTo promote the collection of outcome data, a letter was sent by registered mail to all families not contacted by telephone after 7 days requesting that they either contact the research nurse by telephone or complete and return a data form focused on the outcome measures.hPrimary analysis using ED outcome data refers to the analysis conducted including all study participants who had ED outcome data available. Primary analysis refers to the analysis performed including only participants who had follow-up data collected.
  • Will Neuroimaging Reveal a Severe Intracranial Injury in This Adult With Minor Head Trauma? The Rational Clinical Examination Systematic Review

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    JAMA. 2015; 314(24):2672-2681. doi: 10.1001/jama.2015.16316

    This Rational Clinical Examination systematic review summarizes the accuracy of symptoms and signs for revealing severe intracranial injury in adults with minor head trauma.

  • JAMA December 22, 2015

    Figure 3: Evaluation of Patients With Potential Head Traumaa

    aThese recommendations are intended to provide general support for decision making and should not replace clinical judgment. CT indicates computed tomography; GCS, Glasgow Coma Scale.bDangerous mechanisms is a pedestrian struck by a vehicle, an occupant ejected for a motor vehicle, or a fall from elevation of more than 1 m or 5 stairs.cThe decision to discharge, observe or order a CT scan depends on the setting, clinician’s judgement about the likelihood of injury, patient preference, number of features present, and the particular features present.dThe Canadian CT Head Rule includes age 65 years or older, dangerous mechanism, vomiting more than once, amnesia for more than 30 minutes, GCS score of less than 15 at 2 hours, or a skull fracture.eThe New Orleans Criteria includes older than 60 years, intoxication, headache, any vomiting, seizure, amnesia, visible trauma above the clavicle.
  • Transcatheter Aortic Valve Implantation in Failed Bioprosthetic Surgical Valves

    Abstract Full Text
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    JAMA. 2014; 312(2):162-170. doi: 10.1001/jama.2014.7246

    Dvir and coauthors evaluated data from a multinational valve-in-valve implantation registry to determine survival among patients after transcatheter valve-in-valve implantation inside failed surgical bioprosthetic valves.

  • JAMA March 6, 2013

    Figure 1: Derivation of the Study Cohort

    aSignificant coronary artery disease was defined as >50% luminal stenosis in any epicardial coronary artery on angiography. Athletic heart was defined as left ventricular dilatation with preserved/mildly reduced ejection fraction and high stroke volume, on a background of regular organized endurance training, with raised maximal oxygen uptake on cardiopulmonary exercise testing. Significant primary valvular disease was defined as moderate or higher valvular stenosis/regurgitation, with the exception of functional mitral regurgitation. Functional mitral regurgitation was defined as mitral regurgitation secondary to left ventricular remodeling resulting in failure of leaflet coadaptation, in the setting of normal mitral valve anatomy, on echocardiography and cardiovascular magnetic resonance imaging.
  • Effect of Not Monitoring Residual Gastric Volume on Risk of Ventilator-Associated Pneumonia in Adults Receiving Mechanical Ventilation and Early Enteral Feeding: A Randomized Controlled Trial

    Abstract Full Text
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    JAMA. 2013; 309(3):249-256. doi: 10.1001/jama.2012.196377
    In a randomized trial, Reignier and coauthors assess the risk that ventilator-associated pneumonia (VAP) is not increased when residual gastric volume is not monitored vs routine monitoring in 452 patients receiving invasive mechanical ventilation and early enteral nutrition. In an Editorial, Rice discusses enteral feeding in critically ill patients.
  • JAMA June 9, 2010

    Figure: Explanation of Additional Symptoms of Intracerebral Hemorrhage

    In the top panel, a small hemorrhage in the right basal ganglia causes left hemiparesis and a clinical presentation indistinguishable from ischemic stroke. As intracerebral bleeding continues (middle panel), expansion of the hemorrhage exerts a mass effect on the brain, increasing intracranial pressure and causing a midline shift. Clinical findings characteristic of hemorrhagic stroke manifest, such as progressive neurological deficits, headache, and vomiting. Eventually, blood may dissect into the ventricles and extend into the subarachnoid space via the median and lateral apertures of the fourth ventricle (bottom panel), leading to neck stiffness. In severe hemorrhagic stroke, intracerebral expansion of the hemorrhage may result in coma from bilateral cerebral dysfunction or uncal herniation.
  • Norovirus Outbreak Associated With Ill Food-Service Workers—Michigan, January-February 2006

    Abstract Full Text
    JAMA. 2008; 299(2):164-166. doi: 10.1001/jama.299.2.164
  • JAMA September 13, 2006

    Figure: Suggested Algorithm for the Approach to Headache

    *POUNDing: Pulsatile quality; duration 4-72 hOurs; Unilateral location; Nausea and vomiting; Disabling intensity. †Cluster-type headache, abnormal findings on neurologic examination, undefined headache (ie, not cluster-, migraine-, or tension-type), headache with aura, headache aggravated by exertion or valsalva-like maneuver, headache with vomiting.
  • Local Transmission of

    Abstract Full Text
    JAMA. 2003; 290(22):2931-2934. doi: 10.1001/jama.290.22.2931
  • Magazine Ideals Wrong

    Abstract Full Text
    JAMA. 2001; 286(4):409-409. doi: 10.1001/jama.286.4.409-JQU10006-3-1
  • JAMA December 6, 2000

    Figure 2: Distribution of the Total Emesis Episodes Per Person During the 5-Day Study Period by Treatment Groups

    The lines inside the box represent the median values. The lower and upper borders of the boxes represent the 25th and 75th percentiles. The interquartile range is the height of the box. The whisker lines extend from the box borders to data points that are less than or equal to 1.5 interquartile ranges. Circles outside the whisker lines represent extreme values. P values are based on pairwise tests using the Wilcoxon rank-sum test.
  • Electroacupuncture for Control of Myeloablative Chemotherapy–Induced Emesis: A Randomized Controlled Trial

    Abstract Full Text
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    JAMA. 2000; 284(21):2755-2761. doi: 10.1001/jama.284.21.2755
  • JAMA April 26, 2000

    Figure 3: Reasons Given by Nighttime Caregivers for Choosing Infant Sleep Position

    SIDS indicates sudden infant death syndrome. The following reasons were given for placing infant in the specified position: "doctor or nurse suggested it"; "family member or friend suggested it"; "read about it in newspapers, magazines, or baby care books"; "the baby likes it or sleeps better that way"; tradition—"I sleep that way, my other children slept that way"; "afraid of vomiting, choking or spitting up"; "SIDS, SIDS report, safest." Data are for 1995-1998. Error bars indicate upper limit of 95% confidence interval.
  • Fecal and Oral Shedding of Helicobacter pylori From Healthy Infected Adults

    Abstract Full Text
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    JAMA. 1999; 282(23):2240-2245. doi: 10.1001/jama.282.23.2240
  • Fair Conduct and Fair Reporting of Clinical Trials

    Abstract Full Text
    JAMA. 1999; 282(18):1766-1768. doi: 10.1001/jama.282.18.1766
  • It's Over, Debbie

    Abstract Full Text
    JAMA. 1988; 259(2):272-272. doi: 10.1001/jama.259.2.272