This systematic review to support the 2016 update of the US Preventive Services Task Force Recommendation Statement on screening for colorectal cancer summarizes published evidence about the effectiveness of routine screening, accuracy of screening tests and strategies, and potential screening harms.
This simulation study uses Kaiser Permanente patient data to estimate benefits, complications, and costs of colorectal cancer screening stratified by adenoma detection rate and age at initiation.
This study characterizes the quality of clinical studies and data used to support US Food and Drug Administration approval of modifications to high-risk medical devices.
To investigate the safety of metoclopramide use in pregnancy, Pasternak and coauthors conducted a register-based cohort study of 1 222 503 pregnancies in Denmark, using matched analyses to estimate risks of major congenital malformations overall as well as risks of spontaneous abortion and stillbirth.
This review summarizes advances in risk classification methods, imaging techniques, biomarkers for diagnosis, and treatments for prostate cancer.
This Evidence Report to support a 2016 US Preventive Services Task Force Recommendation Statement summarizes evidence on the benefits and harms of screening for obstructive sleep apnea in asymptomatic adults.
Omuro and DeAngelis review the clinical management of malignant gliomas, including genetic and environmental risk factors such as cell phones, diagnostic pitfalls, symptom management, specific antitumor therapy, and common complications.
Deppen and coauthors report on the accuracy of positron emission tomography (PET) combined with 18-fluorodeoxyglucose (FDG) to diagnose lung cancer in areas with infectious lung disease.
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