This cohort study compares the ability of the quick Sequential Organ Failure Assessment score vs systemic inflammatory response syndrome and severe sepsis criteria for a in-hospital mortality risk among adult patients presenting to the emergency department with suspected infection.
This randomized clinical trial compares the effects of hydrocortisone vs placebo on development of septic shock among intensive care patients with severe sepsis who were not in septic shock.
Kaukonen and coauthors describe changes in mortality from 2000 to 2012 for severe sepsis with and without shock in 101 064 patients in 171 intensive care units in Australia and New Zealand. In an Editorial, Iwashyna and Angus discuss the challenge of determining changes in the epidemiology of severe sepsis and evaluating improvements in quality of care.
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