This international randomized clinical trial found that among adults with Gaucher disease type 1, treatment with eliglustat for 9 months resulted in significant improvements in spleen volume, hemoglobin level, liver volume, and platelet count compared with placebo.
A 67-year-old woman presented with fatigue for 4 weeks; a history of type 2 diabetes mellitus, hypertension, hyperlipidemia, and allergic rhinitis; and leukocytosis with predominant granulocytes. What’s the diagnosis?
This randomized trial reports that among patients with severe trauma and major bleeding, early administration of plasma, platelets, and red blood cells in a 1:1:1 ratio compared with a 1:1:2 ratio did not result in significant differences in mortality at 24 hours or at 30 days.
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