Showing 1 – 20 of 103
Relevance | Newest | Oldest |
  • Biomedical Informatics in the Education of Physicians

    Abstract Full Text
    JAMA. 2010; 304(11):1227-1228. doi: 10.1001/jama.2010.1262
  • Drugs and Therapeutics in the Age of the Genome

    Abstract Full Text
    free access
    JAMA. 2000; 284(21):2786-2787. doi: 10.1001/jama.284.21.2786-JMS1206-4-1
  • Value of Personalized Medicine

    Abstract Full Text
    JAMA. 2016; 315(6):612-613. doi: 10.1001/jama.2015.17130
  • Potential Role of Pharmacogenomics in Reducing Adverse Drug Reactions: A Systematic Review

    Abstract Full Text
    JAMA. 2001; 286(18):2270-2279. doi: 10.1001/jama.286.18.2270
  • Genetic Factors Associated With Severe Cutaneous Adverse Reactions—Reply

    Abstract Full Text
    JAMA. 2014; 312(20):2166-2166. doi: 10.1001/jama.2014.14148
  • Molecular Autopsy for Sudden Unexpected Death

    Abstract Full Text
    free access
    JAMA. 2016; 316(14):1492-1494. doi: 10.1001/jama.2016.11445

    This case series describes the diagnostic yield of whole-exome sequencing (molecular autopsy) performed postmortem on patients younger than 45 years who died unexpectedly.

  • Genetic Variants Associated With Phenytoin-Related Severe Cutaneous Adverse Reactions

    Abstract Full Text
    free access
    JAMA. 2014; 312(5):525-534. doi: 10.1001/jama.2014.7859

    Chung and coauthors conducted a case-control study in populations from Taiwan, Japan, and Malaysia and a genome-wide association study to investigate the genetic factors associated with phenytoin-related severe cutaneous adverse reactions.

  • Digital Medical Tools and Sensors

    Abstract Full Text
    JAMA. 2015; 313(4):353-354. doi: 10.1001/jama.2014.17125

    In this Viewpoint, Eric Topol and colleagues discuss the effect that mobile devices as biomedical sensors could have on health care.

  • Scientists Scan Genome for Autism Clues

    Abstract Full Text
    JAMA. 2007; 297(12):1303-1304. doi: 10.1001/jama.297.12.1303
  • Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records

    Abstract Full Text
    free access
    JAMA. 2016; 315(1):47-57. doi: 10.1001/jama.2015.17701

    This prospective cohort study investigates the association of rare, potentially pathogenic variants in 2 cardiac arrhythmia susceptibility genes with arrhythmia and electrocardiographic phenotypes using electronic medical record data.

  • Association Between Use of Interferon Beta and Progression of Disability in Patients With Relapsing-Remitting Multiple Sclerosis

    Abstract Full Text
    free access has multimedia
    JAMA. 2012; 308(3):247-256. doi: 10.1001/jama.2012.7625
    Shirani and coauthors analyzed data from 2656 patients with relapsing-remitting multiple sclerosis in British Columbia from 1985 to 2008 to investigate whether treatment with interferon beta was associated with a reduction in disability progression. In an Editorial, Derfuss and Kappos discuss interferon’s potential benefits in MS.
  • CYP2C19 Genotype, Clopidogrel Metabolism, Platelet Function, and Cardiovascular Events: A Systematic Review and Meta-analysis

    Abstract Full Text
    free access is expired quiz
    JAMA. 2011; 306(24):2704-2714. doi: 10.1001/jama.2011.1880
  • Genetics

    Abstract Full Text
    JAMA. 2003; 289(20):2723-2724. doi: 10.1001/jama.289.20.2723
  • Histology

    Abstract Full Text
    JAMA. 2003; 289(13):1707-1708. doi: 10.1001/jama.289.13.1707-a
  • β 2 -Adrenergic Receptor Genotype and Survival Among Patients Receiving β-Blocker Therapy After an Acute Coronary Syndrome

    Abstract Full Text
    free access
    JAMA. 2005; 294(12):1526-1533. doi: 10.1001/jama.294.12.1526
  • How to Use an Article About Genetic Association: A: Background Concepts

    Abstract Full Text
    JAMA. 2009; 301(1):74-81. doi: 10.1001/jama.2008.901
  • Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy

    Abstract Full Text
    free access
    JAMA. 2009; 302(8):849-857. doi: 10.1001/jama.2009.1232
  • The Anatomy of the Human Genome: A Neo-Vesalian Basis for Medicine in the 21st Century

    Abstract Full Text
    JAMA. 2001; 286(18):2289-2295. doi: 10.1001/jama.286.18.2289
  • Clinical Interpretation and Implications of Whole-Genome Sequencing

    Abstract Full Text
    free access
    JAMA. 2014; 311(10):1035-1045. doi: 10.1001/jama.2014.1717

    Dewey and colleagues found that depending on the sequencing platform used, there was incomplete coverage of inherited disease genes, low reproducibility of potentially clinically significant genetic variation, and uncertainty about clinically reportable findings.

  • Implications of the Human Genome Project for Medical Science

    Abstract Full Text
    free access
    JAMA. 2001; 285(5):540-544. doi: 10.1001/jama.285.5.540