This randomized clinical trial compares the effect of lorazepam vs placebo added to haloperidol for persistent agitation in patients with advanced cancer and delirium.
This Viewpoint discusses the case of Charlie Gard, a young boy with severe mitochondrial disease on life support in the United Kingdom, and the issues at stake in the conflict between his parents’ wishes to pursue expensive, unproven treatment and the UK National Health Service’s insistence on a palliative approach.
This Arts and Medicine essay reviews Extremis, a 2016 short documentary streaming on Netflix, which addresses the challenges of end-of-life communication and decision-making in the ICU by following the work and patients of a critical and palliative care physician at Highland Hospital in Oakland, California.
This meta-analysis of clinical trials article assesses the effects of palliative care interventions on patient quality of life, symptom burden, and survival and on caregiver burden and satisfaction.
This randomized trial assesses the effect of an inpatient palliative care intervention vs standard transplant care on quality of life during hospitalization for patients undergoing hematopoietic stem cell transplantation (HCT).
This Viewpoint discusses the characteristics of palliative care and population health and describes how synergies between these disciplines might improve quality of care, especially for older persons with life-limiting illnesses.
This Viewpoint calls for increased research funding and focus on palliative care as a twin approach when initiating cancer-directed treatment as soon as patients receive their diagnosis.
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