This randomized clinical trial compares the efficacy of 4 oral combination analgesics among adult patients treated for moderate to severe acute extremity pain at 2 urban emergency departments in the United States.
A comprehensive urine drug screen for a 50-year-old woman taking daily methadone, immediate-release morphine, gabapentin, duloxetine, and celecoxib for pain was positive for methadone and morphine but also codeine and hydromorphone. How do you interpret the results?
This Viewpoint discusses the president’s recent declaration of a public health emergency in response to the opioid crisis in the United States.
In this Viewpoint, authors from the US CDC’s National Center for Injury Prevention and Control discuss infrastructure investments, legal changes, and clinical and public health strategies for reducing overdose deaths among opioid users.
A 53-year-old woman with chronic low back pain presented for a prescription refill of hydrocodone/acetaminophen. She had partial paralysis from a thoracic spinal cord infarction secondary to aortic dissection from prior cocaine use and reported taking hydrocodone on that day but no recent illicit drug use. Urine immunoassay drug screen results were negative overall but positive for cocaine. How would you proceed?
This study uses US National Vital Statistics mortality data to assess change in US life expectancy from 2000 to 2015 attributable to opioid-involved poisonings.
This study uses Medicaid data to compare prescription opioid use, duration of opioid use, and rates of medication-assisted treatment (buprenorphine, methadone, or naltrexone) among enrollees before and after an overdose event.
This Viewpoint describes the National Academies of Sciences, Engineering, and Medicine’s new report on the harms associated with opioid misuse and the effects of strategies to reduce those harms, and discusses the importance of balancing patients’ pain management and addressing the current opioid epidemic.
This Viewpoint argues that abandoning opioids on principal may be premature and could harm patients successfully treating their chronic pain with opioids.
This study uses insurance claims and HCAHPS data to investigate correlations between measures of pain and patient satisfaction after hospital discharge and postoperative opioid prescriptions.
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