A 66-year-old man developed noninfectious fever and rash after autologous HSCT. Chest computed tomography showed ground-glass and consolidative lung opacities; skin punch biopsy showed vacuolar change and superficial perivascular mononuclear cell infiltrate. What would you do next?
An 80-year-old man with stage 4 chronic kidney disease, 2 days of anuria, and an elevated serum κ to λ free light chain ratio had a bone marrow biopsy that stained positive for the plasma cell marker CD138. What would you do next?
This cancer epidemiology study uses National Center for Health Statistics population data to estimate trends in age-standardized cancer mortality rates by US county between 1980 and 2014.
This noninferiority trial compares the effects of zoledronic acid administered every 12 weeks vs every 4 weeks over 2 years on prevention of skeletal events in patients with bone metastases due to breast cancer, prostate cancer, or multiple myeloma.
This Viewpoint discusses ethical issues related to rapid access to investigational agents (compassionate use) and outlines a patient-focused approach to responding to compassionate use requests.
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