In this cohort study, there was no survival difference at 15 years among older patients who underwent mechanical prosthetic vs bioprosthetic mitral replacement.
In a randomized clinical trial involving 241 patients undergoing transcatheter aortic valve replacement, Abdal-Wahab and co-authors found that use of balloon-expandable valves resulted in a greater rate of device success than use of self-expandable valves.
To report the initial US experience with newly approved transcatheter aortic valve replacement, Mack and coauthors gathered outcome data, including all-cause in-hospital mortality and stroke, from 7710 cases in 224 participating US registry hospitals. Bonow comments in an editorial.
Suri and coauthors ascertain the comparative effectiveness of initial medical management (nonsurgical observation) vs early mitral surgery following the diagnosis of mitral regurgitation due to ruptured chordae tendineae (flail leaflets) in 1021 patients from France, Italy, Belgium, and the United States. In an Editorial, Otto discusses the risks of early surgical intervention and how the new findings influence patient care.
This randomized clinical trial compares the efficacy and adverse effects of 2 cerebral embolic protection devices vs a shared control group in reducing ischemic central nervous system injury during surgical aortic valve replacement.
Marrouche and coauthors report the results of the DECAAF study, which was a multicenter assessment of the association of atrial tissue fibrosis identified by delayed enhancement magnetic resonance imaging (MRI) and catheter ablation outcomes in patients with atrial fibrillation.
In this follow-up study of a US registry of patients undergoing transcatheter aortic valve replacement, 1-year outcomes included overall mortality of 23.7%, stroke rate of 4.1%, and a composite of death and stroke of 26.0%.
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