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  • Treatment Indications for Antidepressants Prescribed in Primary Care in Quebec, Canada, 2006-2015

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    JAMA. 2016; 315(20):2230-2232. doi: 10.1001/jama.2016.3445

    This pharmacoepidemiology study uses national Canadian electronic medical record data to describe treatment indications for antidepressants and temporal trends in antidepressant prescribing for depression in Quebec, Canada, from 2006 through 2015.

  • JAMA November 24, 2015

    Figure 2: Timing of the First and Subsequent Migraine Attacks During the 3 Months Following ASD Closure

    The first vertical column of data markers on the left indicates day 1. Day 0 was the day of ASD closure.
  • Glioblastoma and Other Malignant Gliomas: A Clinical Review

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    JAMA. 2013; 310(17):1842-1850. doi: 10.1001/jama.2013.280319

    Omuro and DeAngelis review the clinical management of malignant gliomas, including genetic and environmental risk factors such as cell phones, diagnostic pitfalls, symptom management, specific antitumor therapy, and common complications.

  • Still No Migraine Relief for Kids

    Abstract Full Text
    JAMA. 2016; 316(24):2589-2589. doi: 10.1001/jama.2016.19352
  • The State of US Health, 1990-2010: Burden of Diseases, Injuries, and Risk Factors

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    JAMA. 2013; 310(6):591-606. doi: 10.1001/jama.2013.13805

    The US Burden of Disease Collaborators used a systematic analysis of descriptive epidemiology of diseases and injuries, their sequelae, and risk factors or clusters of risk factors from 1990 to 2010 to describe the health status of the United States. In an editorial, Fineberg discusses the health of the US population.

  • Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism

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    JAMA. 2013; 309(16):1696-1703. doi: 10.1001/jama.2013.2270
    To determine whether prenatal exposure to valproate is associated with an increased risk of autism spectrum disorder and childhood autism in offspring, Christensen and coauthors conducted a population-based study of all children born alive in Denmark from 1996 to 2006. Meador and Loring provide comment in the related Editorial.
  • US Spending on Personal Health Care and Public Health, 1996-2013

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    JAMA. 2016; 316(24):2627-2646. doi: 10.1001/jama.2016.16885

    This study used data from National Health Expenditure Accounts to estimate US spending on personal health care and public health, according to condition, age and sex group, and type of care.

  • 23andMe, Big Data, and the Genetics of Depression

    Abstract Full Text
    JAMA. 2017; 317(1):14-16. doi: 10.1001/jama.2016.14136

    This Medical News article discusses the use of consumer data for disease genomics research.

  • JAMA April 4, 2007

    Figure: Flow of Participants Through the Trial

    Reasons for nonevaluable data were failure to return diary cards, which resulted in an absence of efficacy data for analysis, or taking other migraine medications prior to treating with study medication, which confounded outcomes.
  • JAMA July 19, 2006

    Figure 1: Age-Adjusted Cumulative Incidence of Major CVD According to Migraine Status

    Major cardiovascular disease (CVD) was defined as the first occurrence of any of the following events: nonfatal ischemic stroke, nonfatal myocardial infarction, or ischemic CVD death. Mean (SD) of follow-up, 9.9 (1.2) years. An incidence curve is not shown for women with prior migraine (women who indicated a history of migraine but no active migraine in the previous year; n = 1515).
  • JAMA July 4, 2007

    Figure: Studies Suggest New Approaches to Pain

    Studies of the mechanisms of migraine and rare pain disorders are inspiring the search for analgesics that selectively target pain sources.
  • Migraine Headache

    Abstract Full Text
    JAMA. 2000; 284(20):2672-2672. doi: 10.1001/jama.284.20.2672
  • Prevention of Migraine

    Abstract Full Text
    JAMA. 2017; 317(21):2230-2231. doi: 10.1001/jama.2017.1680

    This Medical Letter review summarizes classes of drugs and other treatments approved by the US Food and Drug Administration for the prevention of migraine.

  • JAMA February 25, 2004

    Figure 2: Change From Baseline in Monthly Migraine Frequency

    Change from baseline is the least squares mean (SE). Linear model P values are vs placebo. Migraine frequency was assessed in terms of migraine periods, which were defined as any occurrence of migraine headache that started, ended, or recurred within 24 hours.
  • JAMA February 25, 2004

    Figure 4: Change From Baseline in Migraine Days per Month

    Change from baseline is the least squares mean (SE). Linear model P values are vs placebo.
  • Migraine on the Rise

    Abstract Full Text
    JAMA. 1999; 282(20):1908-1908. doi: 10.1001/jama.282.20.1908-JQU90009-4-1
  • Insomnia

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    JAMA. 2013; 309(7):706-716. doi: 10.1001/jama.2013.193
    Using the case of a 51-year-old woman with insomnia that began at age 35 years, Buysse reviews the assessment, diagnosis, and treatment of insomnia in adults.
  • JAMA November 14, 2012

    Figure 2: Geographical Location of All Individual Deep White Matter Hyperintensities Projected on Transparent 3-Dimensional Maps After Normalization of the Individual Magnetic Resonance Scans With Segmented Lesions to Standard Montreal Neurological Institute Space

    The upper 2 rows display hyperintensities per study group at baseline and follow-up separately; the lower rows show the difference (ie, progression) between baseline and follow-up in 3 directions. For visualization purposes, lesions are displayed after correction for group size, by adjusting their transparency level with a factor 0.69 for women in the migraine group with migraine with aura (n = 52/n = 75) and 0.91 for female participants with migraine without aura (n = 52/n = 57), using women in the control group as a reference.
  • Infantile Colic and Migraine

    Abstract Full Text
    JAMA. 2013; 309(15):1636-1637. doi: 10.1001/jama.2013.3873
  • Administration of Spores of Nontoxigenic Clostridium difficile Strain M3 for Prevention of Recurrent C difficile Infection: A Randomized Clinical Trial

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    JAMA. 2015; 313(17):1719-1727. doi: 10.1001/jama.2015.3725

    This phase 2 randomized trial reports that spores of nontoxigenic Clostridium difficile strain M3 were well tolerated, appeared to be safe, and reduced recurrence of C difficile infection (CDI) among patients who had previously had CDI treated with metronidazole or vancomycin.