This Viewpoint discusses variances in cardiovascular prevention guidelines from the United States, Europe, and Canada and the debate surrounding low-density lipoprotein levels as the primary focus.
A 62-year-old woman presented with a 6-month history of hair thinning, itchy scalp, and cold sensitivity, has a mild elevation of her thyroid-stimulating hormone level (4.88 mIU/L) and elevated levels of low-density lipoprotein (155 mg/dL) and total cholesterol (257 mg/dL). How do you interpret the test results?
This meta-analysis of genetic association studies summarizes associations between molecular targets of lipid-lowering therapy and risk of type 2 diabetes and coronary artery disease.
This Viewpoint anticipates widespread premature use of proprotein convertase subtilisin-kexin type 9 (PCSK-9) inhibitors in response to the challenges some patients experience taking statins and urges caution until trials and experience demonstrate the new drugs are safe.
Ikeda and coauthors determine whether daily, low-dose aspirin reduces the incidence of cardiovascular (CV) events compared with no aspirin in older Japanese patients with multiple atherosclerotic risk factors.
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