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  • JAMA September 1, 2015

    Figure: Walking Patterns in Individuals With Parkinson Disease With and Without a History of Falls

    Peaks in the graphs are proportional to the amount of time spent with one gait pattern. Parkinson disease patients with a history of falls walked with a less consistent walking pattern, as reflected in the reduced height and increased width of the mountain plots (derived from a transform of the raw signal into the frequency domain). Parkinson disease patients with more consistent gait patterns were less likely to fall. Peaks in the graph are proportional to the regularity and stability of the gait pattern, which are measured repeatedly as a function of time. Copyright 2014, Weiss et al, from which this figure was republished.
  • Intuitive Control of a Powered Prosthetic Leg During Ambulation: A Randomized Clinical Trial

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    JAMA. 2015; 313(22):2244-2252. doi: 10.1001/jama.2015.4527

    This randomized crossover clinical trial reports preliminary data on the effect of including electromyographic data and historical information from prior gait strides in a real-time control system for a powered prosthetic leg during ambulation.

  • The Lady in Mauve : Lyonel Feininger

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    JAMA. 2014; 312(17):1722-1723. doi: 10.1001/jama.2013.279811
  • Cognitive Effects of Konzo

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    JAMA. 2013; 309(19):1985-1985. doi: 10.1001/jama.2013.4960
  • The Patient Who Falls: “It's Always a Trade-off”

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    JAMA. 2010; 303(3):258-266. doi: 10.1001/jama.2009.2024
  • Medical Care for the Final Years of Life: “When You're 83, It's Not Going to Be 20 Years”

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    JAMA. 2009; 302(24):2686-2694. doi: 10.1001/jama.2009.1871
  • JAMA March 5, 2008

    Figure: Physical Findings on Examination of Mr E's Hands and Gait

    A, examination of Mr E's hands showed atrophy of the intrinsic muscles and claw deformities of the fourth and fifth fingers. B, Mr E was unable to maintain a tandem gait. (See video
  • Will My Patient Fall?

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    JAMA. 2007; 297(1):77-86. doi: 10.1001/jama.297.1.77
  • JAMA May 10, 2000

    Figure 3: Scandinavian Stroke Scale Total Score During the First Week of Treatment and at 3 Months

    Scores are adjusted mean total scores (error bars indicate 95% confidence intervals), excluding gait, based on an analysis of variance with pooled study center, age category, pretreatment Scandinavian Stroke Scale score category (for all times except pretreatment), treatment, and treatment-by-center interaction in the model, following a normal score transformation.
  • Effect of Anakinra on Recurrent Pericarditis Among Patients With Colchicine Resistance and Corticosteroid Dependence: The AIRTRIP Randomized Clinical Trial

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    JAMA. 2016; 316(18):1906-1912. doi: 10.1001/jama.2016.15826

    This randomized trial assesses whether anakinra reduces risk of recurrent pericarditis among patients in Italy with colchicine-resistant and corticosteroid-dependent recurrent pericarditis.

  • Evaluation and Treatment of Pericarditis: A Systematic Review

    Abstract Full Text
    JAMA. 2015; 314(14):1498-1506. doi: 10.1001/jama.2015.12763

    This systematic review summarizes published evidence on the causes, diagnosis, therapy, prevention, and prognosis of pericarditis.

  • Colchicine for Prevention of Postpericardiotomy Syndrome and Postoperative Atrial Fibrillation: The COPPS-2 Randomized Clinical Trial

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    JAMA. 2014; 312(10):1016-1023. doi: 10.1001/jama.2014.11026

    Imazio and coauthors conducted a randomized clinical trial among 360 patients undergoing cardiac surgery to determine the efficacy and safety of perioperative use of oral colchicine in reducing postpericardiotomy syndrome, postoperative atrial fibrillation, and postoperative pericardial effusions.

  • JAMA May 28, 2014

    Figure: Prevalence of Either Disability for Activities of Daily Living or Mobility Disability by Usual Gait Speed Among Men Aged 80 Years (N = 6534)

    ADL indicates activities of daily living. Based on data from Guralnik and colleagues.
  • JAMA April 23, 2014

    Figure 4: Algorithm for the Treatment of Parkinson Disease With Predominant Postural Instability and Gait Impairment

    aSuboptimal benefit is defined as improvement in parkinsonian symptoms following initiation of therapy, but the patient still experiences a bothersome or disabling degree of symptoms either continuously or intermittently. In these cases, increase the dose of current medication if the patient is not receiving a maximal dose or add another medication. If benefit is absent, stop the current medication and try another.bIf the patient experiences inadequate symptom control while on current therapy and there was more than 1 treatment option in the previous step, go back to previous step and try an alternate treatment option. If all options in the previous step fail to provide adequate symptom control, move to the next step in the algorithm.cPersistent ambulatory problems including freezing, postural instability, and falls despite optimal dopaminergic therapy are generally refractory to other treatments. Trials of amantadine or a cholinesterase inhibitor, added to ongoing dopaminergic therapy for other symptoms of Parkinson disease, can be considered.dConsider deep brain stimulation if motor fluctuations are refractory to medical therapy and postural instability and/or gait impairment remains responsive to levodopa.
  • Progressive Confusion, Memory Loss, and Gait Ataxia in an Adult

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    JAMA. 2012; 307(20):2195-2196. doi: 10.1001/jama.2012.3447
  • Gait Speed and Survival in Older Adults

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    JAMA. 2011; 305(1):50-58. doi: 10.1001/jama.2010.1923
  • Role of Gait Speed in the Assessment of Older Patients

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    JAMA. 2011; 305(1):93-94. doi: 10.1001/jama.2010.1970
  • Gait Analysis: Normal and Pathological Function

    Abstract Full Text
    JAMA. 2010; 304(8):907-907. doi: 10.1001/jama.2010.1210