This analysis evaluates the potential causal association between genetic variants related to elevated serum calcium levels and risk of coronary artery disease and myocardial infarction using mendelian randomization.
This cross-sectional study examines whether rare and common variants in the lipoprotein lipase gene are associated with early-onset coronary artery disease.
This randomized clinical trial compares the effects of evolocumab vs placebo on change in percent atheroma volume among adult patients with angiographic coronary disease despite treatment with statins.
This meta-analysis of data from 5 population-based cohort studies assesses the associations between coronary artery calcium (CAC) score and atherosclerotic cardiovascular disease (CVD) in low-risk women and the changes in risk discrimination when CAC score is added to traditional CVD risk factors.
This meta-analysis of genetic association studies summarizes associations between molecular targets of lipid-lowering therapy and risk of type 2 diabetes and coronary artery disease.
A 53-year-old man with chest pain and treated hypertension undergoes an exercise treadmill test, which demonstrates 1.5-mm ST-segment depression in inferolateral leads during recovery. How do you interpret the test result?
This retrospective analysis reports that there were no significant differences between physicians with time-limited vs time-unlimited board certification on 10 primary care performance measures.
This randomized clinical trial reports that use of coronary computed tomography angiography to screen for coronary artery disease is not supported among asymptomatic patients with type 1 or type 2 diabetes.
This Viewpoint discusses the use of screening coronary computed tomographic angiography in asymptomatic patients with diabetes.
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