J.-K. Lee and coauthors performed a systematic review and meta-analysis to determine the association between survival and first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors vs chemotherapy among patients with advanced non–small cell lung cancer with wild-type EGFR.
This JAMA Clinical Evidence Synopsis summarizes a Cochrane review of the accuracy of rapid diagnostic tests for detecting P vivax and nonfalciparum malaria in endemic countries.
This randomized trial reports high rates of sustained virologic response in the first part of a open-label study of ombitasvir, paritaprevir (co-dosed with ritonavir), and dasabuvir with ribavirin for 63 patients with hepatitis C virus genotype 1 and human immunodeficiency virus 1 co-infection.
This Medical News & Perspectives article reports on maternity leave in the United States compared with other industrialized countries and how these practices affect the health of new mothers and their infants.
This randomized clinical trial compares the overall response rate and safety of a proposed trastuzumab biosimilar vs trastuzumab and a taxane among women with ERBB2 (HER2)–positive metastatic breast cancer.
This Recommendation Statement from the US Preventive Services Task Force recommends interventions including professional and peer support and formal education during pregnancy and after birth to support breastfeeding.
This meta-analysis summarizes evidence about associations between timing of allergenic food introduction during infancy and risk of allergic or autoimmune disease.
This systematic review to support the 2016 update of the US Preventive Services Task Force Recommendation Statement on screening for colorectal cancer summarizes published evidence about the effectiveness of routine screening, accuracy of screening tests and strategies, and potential screening harms.
This Clinical Evidence Synopsis summarizes a Cochrane review on the efficacy of pharmacological and nonpharmacological interventions for patients with Parkinson disease experiencing fatigue.
This Evidence Report to support an update of the 2008 US Preventive Services Task Force Recommendation Statement on interventions to promote and support breastfeeding summarizes current evidence on benefits and harms of interventions during pregnancy and after birth.
This randomized clinical trial assesses the effectiveness of a nursing quality improvement intervention and a mobile health messaging intervention separately and combined to promote infant safe sleep practices compared with control breastfeeding interventions in mothers of healthy term newborns at 16 US hospitals.
This study compares cancer detection and recall rates with digital mammography combined with tomosynthesis vs digital mammography alone in women with dense breasts.
This randomized clinical trial compares the effects of physical rehabilitation vs usual care on length of stay of ICU patients with acute respiratory failure.
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