This Viewpoint reviews the development of immune checkpoint inhibitors as a new drug class for treating cancer, and discusses future directions including development of commercial assays for identifying response-to-treatment biomarkers and the use of combination regimens to improve response.
This Viewpoint reviews evidence documenting an association between overweight and obesity and cancer and discusses the underacknowledged role of weight control counseling and community programs as a cancer prevention strategy.
This JAMA Insights article explains cell-free circulating tumor DNA and its utility in noninvasive cancer detection and characterization, prediction of treatment response, monitoring of disease relapse, and identification of mechanisms of resistance to targeted therapies.
This Medical News article discusses recent advances and challenges in the development of liquid biopsies for cancer management.
This case series of patients with advanced cancer evaluates the proportion and potential clinical implications of inherited variants detected using DNA sequencing of tumor and normal tissue compared with genetic test results based on current guidelines.
This cohort analysis uses Nurses’ Health Study and Health Professionals Follow-Up Study data to examine the association between weight gain in early to middle adulthood and heart disease, cancer, and death later in life.
This Evidence Report to support the 2017 update of the US Preventive Services Task Force Recommendation Statement on screening for thyroid cancer summarizes evidence about the benefits and harms associated with thyroid cancer screening and treatment of early thyroid cancer in asymptomatic adults.
This Medical News story follows up on the recent downgrading of a form of thyroid cancer to a noncancerous neoplasm.
This cohort study evaluates the association between time to colonoscopy after a positive fecal immunochemical test result and risk of colorectal cancer and advanced-stage disease at diagnosis.
This study uses SEER database data to compare thyroid cancer incidence and mortality rates in the United States by cancer type and stage between 1974 and 2013.
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