This 2 × 2 factorial trial compared the effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) vs placebo and of supervised treadmill exercise vs education control on 6-minute walk distance at 12 weeks in patients with peripheral artery disease.
This randomized trial compares the effects of postoperative oral cephalexin-metronidazole vs placebo on frequency of surgical site infection (SSI) in obese women undergoing cesarean delivery.
A 24-year-old woman at 26 weeks’ gestation had a quickly developing vascular nodular mass with friable edges on her upper maxillary gingiva. She has no fever, local trauma, or lymphadenopathy. What would you do next?
This secondary analysis of outcomes from the PREMILOC (Early Low-Dose Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia in Extremely Preterm Infants) trial compares neurodevelopmental impairment in neonates given hydrocortisone vs placebo.
In this Viewpoint, 2016 Lasker Award winners William Kaelin, Peter Ratcliffe, and Gregg Semenza discuss their discovery of pathways by which humans and other multicellular organisms sense and respond to changes in oxygen availability.
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