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JAMA Clinical Challenge

A Florid, Tiny, Discrete Eruption on the Penis

Image of many tiny, smooth, translucent, and glistening papules on the glans penis and prepuce

Hsien-Yi Chiu, MD
Hsien-Ching Chiu, MD
A 13-year-old boy presents for evaluation of asymptomatic papules on his penis for the past month. The number of lesions has increased slowly. He reports no other associated systemic symptoms and neither a preceding sexual exposure nor a history of sexually transmitted disease. A viral infection was suspected in medical clinics, but no improvement was observed after treatments. Clinical examination reveals many tiny, smooth, translucent, and shiny skin-colored papules affecting nearly all the glans penis and prepuce (Figure). A few similar lesions are distributed on the thighs.

See the full article for an explanation and discussion.

Author Affiliations: Drs Hsien-Ching Chiu (hcchiu1003@ntu.edu.tw) and Hsien-Yi Chiu are affiliated with the Department of Dermatology, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan.