http://jama.jamanetwork.com/ en-us Mon, 31 Dec 2012 00:00:00 GMT Tue, 01 Jan 2013 00:49:00 GMT Silverchair editor@jama.jamanetwork.com webmaster@jama.jamanetwork.com http://jama.jamanetwork.com/article.aspx?articleID=1221708 Wed, 25 Jul 2012 00:00:00 GMT Mateen FJ, Mills EJ. <span class="paragraphSection">Although antiretroviral therapy has had a major effect on improving the survival of individuals with human immunodeficiency virus (HIV), cognitive disorders related to HIV remain an important burden of disease and disability worldwide. Among the more than 30 million adults living with HIV worldwide, a substantial proportion is estimated to have some form of HIV-associated neurocognitive disorders encompassing HIV dementia, mild neurocognitive impairment, and asymptomatic neurocognitive impairment. Conservative estimates from better resourced countries suggest that the number of individuals of all ages living with HIV-related cognitive disorders will increase 5- to 10- fold by 2030. Although data from Africa are sparse, 30% of the HIV-infected population in 1 Ugandan outpatient clinic experienced some form of HIV-associated cognitive loss.</span> 308 4 349 350 10.1001/jama.2012.8538 http://jama.jamanetwork.com/article.aspx?articleID=1221708