http://jama.jamanetwork.com/ en-us Sat, 01 Dec 2012 00:00:00 GMT Tue, 01 Jan 2013 00:44:01 GMT Silverchair editor@jama.jamanetwork.com webmaster@jama.jamanetwork.com http://jama.jamanetwork.com/article.aspx?articleID=1367458 Wed, 03 Oct 2012 00:00:00 GMT Hampton T. <span class="paragraphSection">Expression of EPHA4, a receptor previously shown to influence axon growth, was inversely correlated with late disease onset and survival in 158 Dutch patients with amyotrophic lateral sclerosis (ALS), report investigators from Belgium (Van Hoecke A et al. Nat Med. doi:10.1038/nm.2901 [published online August 26, 2012]). EPHA4 binds to ephrins, proteins thought to play a role in synapse formation and regulation of long-term synaptic plasticity and memory.</span> 308 13 1310 1310 10.1001/jama.2012.13154 http://jama.jamanetwork.com/article.aspx?articleID=1367458