Worsening chronic heart failure (HF) is a major public health problem.
To determine the optimal dose and tolerability of vericiguat, a soluble guanylate cyclase stimulator, in patients with worsening chronic HF and reduced left ventricular ejection fraction (LVEF).
Design, Setting, and Participants
JAMA. Published online November 08, 2015. doi:10.1001/jama.2015.15734