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 Showing 1-13 of 13 Articles
Viewpoint  FREE
Lauren S. Hughes, MD, MPH; Alon Peltz, MD, MBA; Patrick H. Conway, MD, MSc
Includes: Supplemental Content
This Viewpoint describes the State Innovation Model initiative, including innovations states have made for health care delivery systems as well as lessons learned.
Viewpoint  FREE
Eli Y. Adashi, MD, MS; Hans Gao, BA; I. Glenn Cohen, JD
This Viewpoint discusses the evolving frequency of hospital-based active shooter incidents, the relevant legal framework, and the role of hospitals and physicians in countering this threat.
Editorial  FREE
Camilla S. Graham, MD, MPH
Hepatitis C virus (HCV) infection causes substantial morbidity and mortality, but patients with human immunodeficiency virus (HIV) co-infection are 3 times more likely to develop cirrhosis or liver decompensation than those infected with hepatitis C alone.1 Unlike the treatment of HIV, for which the goal is viral suppression, treatment of ...
Original Investigation  FREE
Mark S. Sulkowski, MD; Joseph J. Eron, MD; David Wyles, MD; Roger Trinh, MD; Jay Lalezari, MD; Chia Wang, MD; Jihad Slim, MD; Laveeza Bhatti, MD; Joseph Gathe, MD; Peter J. Ruane, MD; Richard Elion, MD; Fritz Bredeek, MD; Robert Brennan, MD; Gary Blick, MD; Amit Khatri, PhD; Krystal Gibbons, BS; Yiran B. Hu, MS; Linda Fredrick, MS; Gretja Schnell, PhD; Tami Pilot-Matias, PhD; Rakesh Tripathi, MS; Barbara Da Silva-Tillmann, MD; Barbara McGovern, MD; Andrew L. Campbell, MD; Thomas Podsadecki, MD
Includes: Supplemental Content

Importance  Patients co-infected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) are at high risk for liver disease progression. However, interferon-based treatments for HCV infection have significant toxicities, limiting treatment uptake.

Objective  To assess the all-oral 3 direct-acting antiviral (3D) regimen of ombitasvir, paritaprevir ...

Editorial: Hepatitis C and HIV Co-infection; Camilla S. Graham, MD, MPH
Original Investigation  FREE
Anu Osinusi, MD, MPH; Kerry Townsend, BA; Anita Kohli, MD, MS; Amy Nelson, RN; Cassie Seamon, RN; Eric G. Meissner, MD, PhD; Dimitra Bon, MS; Rachel Silk, RN; Chloe Gross, RN; Angie Price, NP; Mohammad Sajadi, MD; Sreetha Sidharthan, BS; Zayani Sims, BS; Eva Herrmann, PhD; John Hogan, MD; Gebeyehu Teferi, MD; Rohit Talwani, MD; Michael Proschan, PhD; Veronica Jenkins, MD; David E. Kleiner, MD, PhD; Brad J. Wood, MD; G. Mani Subramanian, MD, PhD; Phillip S. Pang, MD, PhD; John G. McHutchison, MD; Michael A. Polis, MD, MPH; Anthony S. Fauci, MD; Henry Masur, MD; Shyam Kottilil, MD, PhD
Includes: Supplemental Content

Importance  There is an unmet need for interferon- and ribavirin-free treatment for chronic hepatitis C virus (HCV) infection in patients co-infected with human immunodeficiency virus (HIV).

Objective  To evaluate the rates of sustained virologic response (SVR) and adverse events in previously untreated patients with HCV genotype ...

Editorial: Hepatitis C and HIV Co-infection; Camilla S. Graham, MD, MPH
Viewpoint  FREE
JoAnn E. Manson, MD, DrPH; Shari S. Bassuk, ScD
This Viewpoint discusses vitamin D screening and supplemental vitamin D for nonskeletal health benefits in light of existing recommendations and large-scale trials in progress.
JAMA Patient Page  FREE
Jill Jin, MD, MPH
Measles is a very contagious and serious disease. It is also very preventable.
Topics: measles
Viewpoint  FREE
Lawrence O. Gostin, JD
This Viewpoint discusses whether parental objections to mandatory childhood vaccinations justify decisions that place the community at risk.
Medical News & Perspectives  FREE
Bridget M. Kuehn, MSJ
As local and international public health officials work to end the Ebola epidemic in West Africa, efforts to develop therapies and vaccines against the virus are ramping up.
Viewpoint  FREE
Ellen Wright Clayton, MD, JD
This Viewpoint describes an Institute of Medicine report on chronic fatigue syndrome, the result of efforts to develop diagnostic criteria for clinical use and recommend new terminology for the disorder.
Viewpoint  FREE
Janet Corrigan, PhD, MBA; Elliott Fisher, MD, MPH; Scott Heiser, MPH
This Viewpoint describes the coordination of health-related activities at the regional level through such initiatives as accountable health communities and hospital community benefit programs.
Viewpoint  FREE
Allan M. Joseph, BA; Eli Y. Adashi, MD, MS
This Viewpoint discusses tenets of the Consumer Operated and Oriented Plan program and challenges related to its implementation.
George A. Gellert, MD, MPH, MPA; Ricardo Ramirez, LVN; S. Luke Webster, MD
Includes: Supplemental Content
This Viewpoint argues that the increasing use of medical scribers to record patient data will impede the development of electronic health record management systems.

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