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Featured article

Original Investigation | November 24, 2015 FREE  audio icon  video icon

Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy

This randomized trial reports that in patients with proliferative diabetic retinopathy, ranibizumab treatment resulted in visual acuity that was noninferior to panretinal photocoagulation treatment at 2-year follow-up.
Editorial | Medical Letter Review

Featured article

Original Investigation | November 24, 2015

Clopidogrel and Aspirin vs Aspirin Alone in Treating Migraine Headaches

This randomized trial of patients who had no history of migraines compared incidence of migraine attacks between those who used aspirin plus clopidogrel vs aspirin plus placebo for 3 months after undergoing transcatheter atrial septal defect closure.

Original Investigation | November 24, 2015

Intravascular Ultrasound–Guided Drug-Eluting Stent Implantation

This randomized trial assesses the long-term clinical outcomes with intravascular ultrasound–guided drug-eluting stent implantation vs those with angiography-guided implantation in Korean patients with long coronary lesions.

Clinical Review & Education

Featured article

Review | November 24, 2015 CME  video icon

Distal Symmetric Polyneuropathy

This narrative review summarizes current thinking about the diagnosis and treatment of distal symmetric polyneuropathy.


Featured article

Viewpoint | November 23, 2015 FREE ONLINE FIRST

Stakeholder-Driven Comparative Effectiveness Research

This Viewpoint describes how patient, caregiver, clinician, researcher, payer, and industry stakeholders help the Patient-Centered Outcomes Research Institute (PCORI) develop research questions, review research applications, and conduct research.

Viewpoint | November 19, 2015 FREE ONLINE FIRST

Engaging Patients Across the Spectrum of Medical Product Development

In this Viewpoint, the FDA Deputy Commissioner and colleagues describe FDA efforts to integrate patient perspectives and inputs into its regulatory evaluations and decision making, and a conceptual framework for those efforts.

Medical News & Perspectives

Featured article

Medical News & Perspectives | November 25, 2015 FREE ONLINE FIRST

New Approaches to Mitigating Cognitive Decline

This Medical News and Perspectives article explores the biological mechanisms underlying brain resilience that could help inform therapeutic strategies to mitigate cognitive decline.

Explore more articles:  Current Issue | Online First

Multimedia >

Author Interview

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Edward H. Livingston MD, explores the topic of prostate cancer screening in author interviews with: Dan Merenstein about losing a malpractice case despite following evidence-based medicine guidelines (PSA Screening — I Finally Won!). Otis Brawley about Prostate Cancer Incidence and PSA Testing Patterns in Relation to USPSTF Screening Recommendations. David F. Penson about The Pendulum of Prostate Cancer Screening. Victor M. Montori about The Connection Between Evidence-Based Medicine and Shared Decision Making.

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Prostate Cancer Incidence and PSA Testing Patterns in Relation to USPSTF Screening Recommendations

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Article Video

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Neurologic Examination of a Patient With Suspected Distal Symmetric ... (7:43)

Video demonstration of the neurologic examination of a patient with suspected distal symmetric polyneuropathy.

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JAMA Editor's Audio Summary

November 24, 2015

Photocoagulation vs VEGF inhibitor for diabetic retinopathy, ultrasound-guided PCI, global prevalence of low BMI in women, review of polyneuropathy, and more.

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Author Readings
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Reading by Graham McMahon, author of Advancing Continuing Medical Education

Latest Quiz

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Widespread Scaly Eruption in a Patient With Multiple Comorbidities

A 73-year-old woman presented with a widespread scaly pruritic rash lasting 2 months. She had an antinuclear antibody titer of 1:80, elevated SS-A antibodies, a creatinine level of 1.8 mg/dL, and an inflammatory pattern on skin biopsy.

What would you do next?

From The JAMA Network

Doing Less Is Sometimes Enough

JAMA Patient Page

For your patients: Diabetic Neuropathy.

Past JAMA Patient Pages are available in English and Spanish.

A Piece of My Mind

A Hobson’s Choice

JAMA Medical Student Elective in Medical Editing

JAMA offers a 4-week elective in medical editing to third- and fourth-year US medical students. The elective is full-time and must be taken for academic credit. For information and an application, please e-mail jamams@jamanetwork.org.

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Medical News

Cancer Immunotherapy Researchers Refine Checkpoint Blockade Therapies

Visualizing Health Metrics

Cardiovascular Disease Worldwide, 1990-2013

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