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Association Between Hospitalization for Pneumonia and Subsequent Risk of Cardiovascular Disease. Corrales-Medina et al.

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Trends in Use of and Reproductive Outcomes Associated With Intracytoplasmic Sperm Injection. Boulet et al.

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Association of Nonmyeloablative Hematopoietic Stem Cell Transplantation With Neurological Disability in Patients With Relapsing-Remitting Multiple Sclerosis. Burt et al.

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Research

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Chlorhexidine Bathing and Infections

A cluster-randomized crossover trial found that daily bathing of patients in intensive care units with chlorhexidine did not reduce the incidence of health care–associated infections.

Editorial: Daily Chlorhexidine Bathing in ICU

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Sedation Protocol in Critically Ill Pediatric Patients

This cluster randomized trial found that among children undergoing mechanical ventilation for acute respiratory failure, use of a nurse-implemented, goal-directed sedation protocol did not reduce the duration of mechanical ventilation compared with usual care.

Editorial: Protocolized Sedation in Critically Ill Children

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MR/Ultrasound Fusion Biopsy for Prostate Cancer

This diagnostic accuracy study reports that targeted magnetic resonance/ultrasound biopsy, compared with standard ultrasound-guided biopsy, was associated with increased detection of high-risk prostate cancer and decreased detection of low-risk prostate cancer among men undergoing biopsy for suspected prostate cancer.

Editorial: MR/Ultrasound Fusion Biopsy in Prostate Cancer

Medical News: Detecting Prostate Cancer With MRI and Biomarkers

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Opinion

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Digital Medical Tools and Sensors

In this Viewpoint, Eric Topol and colleagues discuss the effect that mobile devices as biomedical sensors could have on healthcare.

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AIDS Treatment

These Viewpoints address the challenges of improving AIDS treatment and prevention globally.

Fauci and Marston on Focusing to Achieve a World Without AIDS

Murray on Antiretroviral Therapy in Developing Countries

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Mandatory Use of Prescription Drug Monitoring Programs

This Viewpoint discusses potential benefits and consequences of requiring physicians who prescribe opioids to register with programs that share data about the prescriptions and dispensing as a way to prevent opioid misuse.

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Optimizing High-Risk Care Management

This Viewpoint proposes principles to guide the design and implementation of care management services for patients with complex comorbidities that put them at high risk for poorly coordinated, low-value care.

Clinical Review & Education

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Diagnosis and Treatment of C difficile in Adults

This systematic review summarizes the diagnosis and treatment of Clostridium difficile infection.

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Decision Curve Analysis

This Guide to Statistics and Methods describes how a decision curve analysis can be used to evaluate the benefits of a diagnostic test, such as 3 prostate biopsy strategies.

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Antiviral Drugs for Seasonal Influenza 2014-2015

This article reviews the antiviral drugs available to treat influenza this season—including oseltamivir and zanamivir—as well as their indications and possible adverse effects.

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Author Interview

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Interview with Peter A. Pinto, MD, author of Comparison of MR/Ultrasound Fusion–Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer

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Comparison of MR/Ultrasound Fusion–Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer

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Video Summary: Medical Applications of 3D Printing Technologies (3:53)

Mark H. Michalski, MD, explains 3D printing and describes the application of this technology in clinical medicine, education, and patient communication.


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JAMA Editor's Audio Summary

January 27, 2015

Chlorhexidine bathing in the ICU, protocolized sedation for children with respiratory failure, MRI for prostate biopsies, C difficile review, and more.

Author Readings
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Reading by Eric Topol, MD, author of Digital Medical Tools and Sensors


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A Crusted Rash in a Patient With AIDS

A 39-year-old man with a recent diagnosis of AIDS (CD4 cell count, 13 cells/μL) was admitted to the hospital for diarrhea and dehydration and was noted to have an intensely pruritic rash with diffuse crust and scale.

What would you do next?

From The JAMA Network

Nonleg Venous Thrombosis in Critically Ill Adults

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Babies With Low Birth Weight

For your patients: Babies With Low Birth Weight.

Past JAMA Patient Pages are available in English and Spanish.

A Piece of My Mind

What I Learned About Adverse Events From Captain Sully

JAMA Medical Student Elective in Medical Editing

JAMA offers a 4-week elective in medical editing to third- and fourth-year US medical students. The elective is full-time and must be taken for academic credit. For information and an application, please e-mail jamams@jamanetwork.org.

Video Translations

International translations of Author Video Interviews

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Author Reading

Eric J. Topol, MD, reads his Viewpoint, Digital Medical Tools and Sensors

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Medical News

Mary L. (Nora) Disis, MD: Ready to Become Editor-in-Chief of the New JAMA Oncology

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