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Since 1883, physicians and health care professionals around the world have turned to JAMA for groundbreaking research and insightful commentary from leaders across the broad spectrum of health care. Subscribe/Learn More

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Research

Featured article

Original Investigation | September 27, 2016

Endovascular Thrombectomy and Outcomes in Ischemic Stroke

This meta-analysis of trials comparing treatment of acute ischemic stroke with vs without endovascular thrombectomy characterizes the threshold time after which treatment is no longer beneficial.
Editorial

Featured article

Original Investigation | September 27, 2016 CME

Association Between Lowering LDL-C and CV Risk Reduction

This meta-analysis compares the association between lowering low-density lipoprotein cholesterol (LDL-C) and cardiovascular (CV) risk reduction for statin vs nonstatin therapies that lower LDL-C.

Featured article

Original Investigation | September 19, 2016 FREE ONLINE FIRST

Medicare Bundled Payments and Joint Replacement

This study evaluates whether the Bundled Payments for Care Improvement initiative of the CMS was associated with a greater reduction in Medicare payments without loss of quality of care for patients with lower extremity joint replacement.
Editorial | Viewpoint

Clinical Review & Education

Featured article

The Rational Clinical Examination | September 27, 2016 CME

Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?

This Rational Clinical Examination systematic review summarizes studies that evaluated the diagnostic accuracy of tests for predicting fluid responsiveness in hemodynamically unstable adult patients to better identify patients who would benefit from further fluid administration.

Opinion

Featured article

Viewpoint | September 22, 2016 FREE ONLINE FIRST

Black Gains in Life Expectancy

This Viewpoint discusses the narrowing life-expectancy gap between the US black and white populations and points out categories of disease and death that could further narrow the gap.

Medical News & Perspectives

Featured article

Medical News & Perspectives | September 21, 2016 FREE ONLINE FIRST

Pharmacogenomics Into the Clinic

This Medical News article discusses barriers to widespread implementation of genotype-guided prescribing.

Explore more articles:  Current Issue | Online First

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Author Interview

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When managing septic shock, passive leg raising is the best test to determine if a patient is likely to respond to a fluid bolus, better than CVP lines or even bedside ultrasound. Dr Najib Ayas, Associate professor of Critical Care Medicine at the University of British Columbia, discusses shock management from the context of his Rational Clinical examination article in the September 27, 2016 issue of JAMA, entitled “Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?”

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RELATED ARTICLE:

Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?

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JAMA Editor's Audio Summary

September 27, 2016

Time-to-thrombectomy and ischemic stroke outcomes, statins vs other LDL-lowering therapies for CV risk reduction, IV fluid resuscitation of shock, and more

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Author Readings
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Reading by Graham McMahon, author of Advancing Continuing Medical Education


Latest Quiz

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Painless Vesicular Eruption on the Dorsal Surfaces of the Hands

A 67-year-old man with a history of heavy smoking and alcohol consumption presented with painless vesicles and milia on the dorsal surfaces of the hands. Results of a basic laboratory tests were normal; liver function tests revealed elevated levels of bilirubin, AST, and ALT.

What would you do next?

From The JAMA Network

A Public Health Perspective on Mental and Medical Comorbidity

JAMA Patient Page
Title

For your patients: Diagnosis and Treatment of Pancreatic Cystic Neoplasms.

Past JAMA Patient Pages are available in English and Spanish.

A Piece of My Mind

It’s Time to Change the Rules

JAMA Medical Student Elective in Medical Editing

JAMA offers a 4-week elective in medical editing to third- and fourth-year US medical students. The elective is full-time and must be taken for academic credit. For information and an application, please email jamams@jamanetwork.org.

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Medical News

Zika: Worse Than Thalidomide?

Visualizing Health Policy

HIV Awareness and Testing, 2013 AND 2014

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Physician Jobs