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In the Media
Effect of Varenicline on Smoking Cessation Through Smoking Reduction: A Randomized Clinical Trial. Ebbert et al.

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Heart Rate and Body Temperature Responses to Extreme Heat and Humidity With and Without Electric Fans. Ravanelli et al.

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Association Between the Use of Fondaparinux vs Low-Molecular-Weight Heparin and Clinical Outcomes in Patients With Non–ST-Segment Elevation Myocardial Infarction. Szummer et al.

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Research

Featured article
Safety of Combining NSAID and Antithrombotic Therapy After MI

This cohort study uses registry data from Denmark to investigate associations between use of NSAIDs and antithrombotic treatment after first-time myocardial infarction, and risk of bleeding and thrombotic events.
Editorial: Nonsteroidal Anti-inflammatory Drugs After Myocardial Infarction

Featured article
Genetic Variant and Vincristine Peripheral Neuropathy in ALL

This genome-wide association study reports an association between a polymorphism in the promoter region of CEP72 and increased risk and severity of vincristine-related peripheral neuropathy among children with acute lymphoblastic leukemia.
Editorial: Precision Medicine to Improve Cancer Care

Author Video Interview   |   JAMA Report Video

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Treating Anticoagulation-Related Intracerebral Hemorrhage

This cohort study investigates associations between reversal of anticoagulation, blood pressure lowering, and resumption of anticoagulation, with rates of hematoma enlargement and ischemic and hemorrhagic events.

Clinical Review & Education

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Use of Lab Tests in Detecting Kidney Disease

This narrative review summarizes current recommendations for measuring glomerular filtration rate and albuminuria to detect and stage kidney disease in adults.

Opinion

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Hospital-Based Active Shooter Incidents

In the wake of the recent in-hospital murder of a Boston cardiothoracic surgeon, this Viewpoint discusses what hospitals and physicians can do to counter the evolving threat of active firearm shootings in hospitals.

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Genomic Engineering and the Future of Medicine

This Viewpoint discusses the implications of genome editing technologies for understanding, treating, and preventing human disease.

Explore more articles:  Current Issue | Online First

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Author Interview

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Interview with William E. Evans, PharmD, author of Association of an Inherited Genetic Variant With Vincristine-Related Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia

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Association of an Inherited Genetic Variant With Vincristine-Related Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia

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Video Summary: Medical Applications of 3D Printing Technologies (3:53)

Mark H. Michalski, MD, explains 3D printing and describes the application of this technology in clinical medicine, education, and patient communication.


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JAMA Editor's Audio Summary

February 24, 2015

Risks of combination NSAIDs-antithrombotics in patients with MI, vincristine-related peripheral neuropathy in children with ALL, management of patients with anticoagulation-induced intracerebral hemorrhage, kidney disease staging, and more.

Author Readings
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Reading by Jennifer Doudna, PhD, author of Genomic Engineering and the Future of Medicine


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Elevated Lactate Levels in a Noncritically Ill Patient

After 5 days of nausea and vomiting, a man in his 60s with advanced, refractory diffuse, large B-cell lymphoma involving the abdomen was seen in the emergency department. Laboratory studies were notable for an elevated lactate level of 6.3 mmol/L (reference range, 0.7-2.2 mmol/L) (56.8 mg/dL; reference range, 6.3-19.8 mg/dL).

How would you interpret the test results?

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Hydroxychloroquine and the Retina

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For your patients: Advance Directives.

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JAMA Medical Student Elective in Medical Editing

JAMA offers a 4-week elective in medical editing to third- and fourth-year US medical students. The elective is full-time and must be taken for academic credit. For information and an application, please e-mail jamams@jamanetwork.org.

Video Translations

International translations of Author Video Interviews

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Jennifer A. Doudna, PhD, reads her Viewpoint, Genomic Engineering and the Future of Medicine

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Medical News

Efforts Seek to Develop Systematic Ways to Objectively Assess Surgeons' Skills

Visualizing Health Policy

Premium Changes in the Affordable Care Act's Health Insurance Marketplaces, 2014-2015

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