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April 23/30, 2014
Vol 311, No. 16
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In the Media
Maternal Body Mass Index and the Risk of Fetal Death, Stillbirth, and Infant Death: A Systematic Review and Meta-analysis. Aune et al.

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Variation in Rates of Autoimmune Thyroid Disease by Race/Ethnicity in US Military Personnel. McLeod et al.

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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors vs Conventional Chemotherapy in Non–Small Cell Lung Cancer Harboring Wild-Type Epidermal Growth Factor Receptor: A Meta-analysis. Lee et al.

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Theme Issue: Neurology


Featured article
Ambulance-Based Thrombolysis in Acute Ischemic Stroke

     This trial reports that acute ischemic stroke patients randomized to prehospital ambulance care received thrombolytic therapy more quickly and often than patients randomized to usual care, without an increase in adverse events.

Editorial: tPA for Stroke

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Improving Outcomes in Acute Ischemic Stroke

     This before-after study reports improvements in time-to-administration of tissue plasminogen activator and all-cause mortality in patients with acute ischemic stroke following implementation of a national quality initiative.

Editorial: tPA for Stroke | Author Video Interview

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Lorazepam vs Diazepam for Pediatric Status Epilepticus

     This randomized trial reports no difference in the efficacy and safety of lorazepam compared to diazepam in the management of pediatric status epilepticus.


Clinical Review & Education

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Pharmacological Treatment of Parkinson Disease  CME

     This narrative review summarizes management of motor and non-motor symptoms and drug adverse effects in patients with Parkinson disease.

Medical News & Perspectives

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Researchers Test Strategies to Prevent Alzheimer Disease

     This news feature reports on recent efforts to develop and test therapies to delay or prevent the onset of Alzheimer disease in cognitively healthy at-risk volunteers.

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Nationwide IV Fluid Shortage Threatens Care

     This News feature reports the consequences on clinical care of a nationwide IV fluid shortage, and discusses possible causes.

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Author Interview

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Interview with Gregg C. Fonarow, MD, author of Door-to-Needle Times for Tissue Plasminogen Activator Administration and Clinical Outcomes in Acute Ischemic Stroke Before and After a Quality Improvement Initiative


Door-to-Needle Times for Tissue Plasminogen Activator Administration and Clinical Outcomes in Acute Ischemic Stroke Before and After a Quality Improvement Initiative

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Neurological Assessment of Case Patients 1 and 2 (04:18)

Case 1, a patient with essential tremor; and case 2, a patient with tremor-dominant Parkinson disease before and after unilateral thalamic deep brain stimulation.

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Waxman Leaves a Mark on Health Policy

During his 20 terms in Congress, Rep Henry Waxman (D, Calif) has had a major influence on US health policy. This timeline highlights many laws he helped shape and how they've changed the US health care system.

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JAMA Editor's Audio Summary

April 22, 2014

JAMA: 2014-04-22, Vol. 311, No. 16,
Editor's Audio Summary

Author Readings
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Reading by Eva Feldman, MD, PhD, author of How Neurologists Can Choose (Even More) Wisely: Prioritizing Waste Reduction Targets and Identifying Gaps in Knowledge

Latest Quiz

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A Nodular Protuberance on the Hard Palate

A 66-year-old man presents with a slowly enlarging growth in his mouth that appeared more than 20 years ago. He denies pain and discomfort but is concerned because the mass has increased in size during the past year.

What would you do next?

From the JAMA Network

Serum Brain-Derived Neurotrophic Factor and the Risk for Dementia

JAMA Patient Page

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For your patients: Warning Signs of a Stroke.

Past JAMA Patient Pages are available in English and Spanish.

A Piece of My Mind


Firearm Violence

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JAMA Medical Student Elective in Medical Editing

JAMA offers a 4-week elective in medical editing to third- and fourth-year US medical students. The elective is full-time and must be taken for academic credit. For information and an application, please e-mail jamams@jamanetwork.org.

Video Translations

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Eva L. Feldman, MD, PhD, reads her Viewpoint, How Neurologists Can Choose (Even More) Wisely

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Visualizing Health Policy

A Snapshot of US Global Health Funding

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JAMA Report Video

Improving Outcomes in Acute Ischemic Stroke

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