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Featured article

Original Investigation | September 22, 2015 FREE CME

Dextromethorphan-Quinidine for Agitation in Patients With Alzheimer Disease

This randomized trial assessed the efficacy and safety of combination dextromethorphan-quinidine to manage agitation among patients with probable Alzheimer disease.

Featured article

Original Investigation | September 22, 2015

Lifestyle-Focused Text Messaging and Coronary Heart Disease

This randomized trial reports that among men with coronary heart disease, use of a lifestyle-focused text messaging service vs usual care resulted in modest improvement in LDL cholesterol levels and greater improvement in other CVD risk factors.

Featured article

Original Investigation | September 22, 2015 CME  audio icon

DNR Status and Neurological Prognosis After In-Hospital Cardiac Arrest

This study of patients successfully resuscitated after an inpatient cardiac arrest assessed whether their postevent do-not-resuscitate staus was appropriate given their neurological prognosis.

Clinical Review & Education

Featured article

From The Medical Letter on Drugs and Therapeutics | September 22, 2015

Alirocumab (Praluent) to Lower LDL-Cholesterol

This Medical Letter review summarizes information about alirocumab, a subcutaneously injected PCSK9 inhibitor, approved for use as an adjunct to statin therapy in patients with clinical atherosclerotic disease requiring further lowering of LDL levels.

Medical News & Perspectives

Featured article

Medical News & Perspectives | September 29, 2015 FREE ONLINE FIRST

Another Frontier in Microbiome Research: Preterm Birth

This Medical News feature describes early research that suggests a possible association between the vaginal microbiome and risk of preterm birth.


Featured article

Viewpoint | October 1, 2015 FREE ONLINE FIRST

Antimicrobials at the End of Life

This Viewpoint discusses the risks and benefits of antimicrobial use at the end of life and calls for goal-directed counseling about infection management in advance care planning.

Featured article

Viewpoint | September 30, 2015 FREE ONLINE FIRST

Evidence-Based Clinical Prevention and Affordable Care Act

This Viewpoint clarifies US Preventive Services Task Force recommendations as they apply to insurance coverage under the Affordable Care Act.

Viewpoint | September 28, 2015 FREE ONLINE FIRST

Review of Priority Review Vouchers

This Viewpoint reviews experience to date with the US Food and Drug Administration’s priority review voucher program, developed to incentivize development of drugs to treat neglected tropical and rare diseases.

Explore more articles:  Current Issue | Online First

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Author Interview

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Interview with Timothy Fendler, MD, MS, author of Alignment of Do-Not-Resuscitate Status With Patients’ Likelihood of Favorable Neurological Survival After In-Hospital Cardiac Arrest

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Alignment of Do-Not-Resuscitate Status With Patients’ Likelihood of Favorable Neurological Survival After In-Hospital Cardiac Arrest

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Article Video

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Extraocular Movements, Heel-to-Shin Test, and Gait Assessment in a ... (1:56)

Neurologic examination of a 64-year-old man with gait instability and diplopia. What would you do next?

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Interactive preview

Video Clip of Patient’s Echocardiogram and Doppler Tracing Through the ...

This interactive includes Doppler echocardiography findings from a patient with a heart murmur. How do you interpret these test results?

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JAMA Editor's Audio Summary

September 22, 2015

Treatment of agitation in Alzheimer disease, text messaging for CV risk modification, a newly approved PCSK9 inhibitor for dyslipidemia, and more.

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Author Readings
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Reading by Graham McMahon, author of Advancing Continuing Medical Education

Latest Quiz

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A Growing Scar on the Abdomen of a Middle-Aged Woman

A woman in her 50s presents for evaluation of a growing, painful scar, with a bruise-like appearance at the periphery, on the right side of her abdomen; she also reports recent fevers, night sweats, nausea, and fatigue.

What would you do next?

From The JAMA Network

Potential Overtreatment of Older, Complex Adults With Diabetes

JAMA Patient Page

For your patients: Flibanserin for Treating Low Sexual Desire in Women.

Past JAMA Patient Pages are available in English and Spanish.

A Piece of My Mind


JAMA Medical Student Elective in Medical Editing

JAMA offers a 4-week elective in medical editing to third- and fourth-year US medical students. The elective is full-time and must be taken for academic credit. For information and an application, please e-mail jamams@jamanetwork.org.

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