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Since 1883, physicians and health care professionals around the world have turned to JAMA for groundbreaking research and insightful commentary from leaders across the broad spectrum of health care. Subscribe/Learn More

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Research

Featured article

Original Investigation | September 27, 2016

Endovascular Thrombectomy and Outcomes in Ischemic Stroke

This meta-analysis of trials comparing treatment of acute ischemic stroke with vs without endovascular thrombectomy characterizes the threshold time after which treatment is no longer beneficial.
Editorial

Featured article

Original Investigation | September 27, 2016 CME

Association Between Lowering LDL-C and CV Risk Reduction

This meta-analysis compares the association between lowering low-density lipoprotein cholesterol (LDL-C) and cardiovascular (CV) risk reduction for statin vs nonstatin therapies that lower LDL-C.

Featured article

Original Investigation | September 19, 2016 FREE ONLINE FIRST

Medicare Bundled Payments and Joint Replacement

This study evaluates whether the Bundled Payments for Care Improvement initiative of the CMS was associated with a greater reduction in Medicare payments without loss of quality of care for patients with lower extremity joint replacement.
Editorial | Viewpoint

Clinical Review & Education

Featured article

The Rational Clinical Examination | September 27, 2016 CME  audio icon

Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?

This Rational Clinical Examination systematic review summarizes studies that evaluated the diagnostic accuracy of tests for predicting fluid responsiveness in hemodynamically unstable adult patients to better identify patients who would benefit from further fluid administration.

Medical News & Perspectives

Medical News & Perspectives | September 30, 2016 FREE ONLINE FIRST

AHRQ Director Sets Course for Agency’s Health Services Research

This Medical News feature transcribes a conversation with the newly appointed director of the Agency for Health Research and Quality (AHRQ), Andrew Bindman, MD, who discusses AHRQ's goals and priorities and the challenges it faces.

Opinion

Viewpoint | September 29, 2016 FREE ONLINE FIRST

Investing Wisely in Health Care Capital

This Viewpoint emphasizes the contribution of capital spending to escalating health care costs, and argues for improved understanding of the ways capital spending, planning, and investment can deliver important gains in health care value and population health.

Featured article

Viewpoint | September 28, 2016 FREE ONLINE FIRST

Lowering the Bar on the Low-Fat Diet

This Viewpoint by David Ludwig assesses the lessons learned from US nutrition recommendations to limit fat intake and the continuing increase in obesity and diabetes and discusses the challenges inherent in scientific evidence regarding nutrition.

Explore more articles:  Current Issue | Online First

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Author Interview

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When managing septic shock, passive leg raising is the best test to determine if a patient is likely to respond to a fluid bolus, better than CVP lines or even bedside ultrasound. Dr Najib Ayas, Associate professor of Critical Care Medicine at the University of British Columbia, discusses shock management from the context of his Rational Clinical examination article in the September 27, 2016 issue of JAMA, entitled “Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?”

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RELATED ARTICLE:

Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?

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JAMA Editor's Audio Summary

September 27, 2016

Time-to-thrombectomy and ischemic stroke outcomes, statins vs other LDL-lowering therapies for CV risk reduction, IV fluid resuscitation of shock, and more

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Author Readings
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Reading by Graham McMahon, author of Advancing Continuing Medical Education


Latest Quiz

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Painless Vesicular Eruption on the Dorsal Surfaces of the Hands

A 67-year-old man with a history of heavy smoking and alcohol consumption presented with painless vesicles and milia on the dorsal surfaces of the hands. Results of a basic laboratory tests were normal; liver function tests revealed elevated levels of bilirubin, AST, and ALT.

What would you do next?

From The JAMA Network

A Public Health Perspective on Mental and Medical Comorbidity

JAMA Patient Page
Title

For your patients: Diagnosis and Treatment of Pancreatic Cystic Neoplasms.

Past JAMA Patient Pages are available in English and Spanish.

A Piece of My Mind

It’s Time to Change the Rules

JAMA Medical Student Elective in Medical Editing

JAMA offers a 4-week elective in medical editing to third- and fourth-year US medical students. The elective is full-time and must be taken for academic credit. For information and an application, please email jamams@jamanetwork.org.

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Medical News

Zika: Worse Than Thalidomide?

Visualizing Health Policy

HIV Awareness and Testing, 2013 AND 2014

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Physician Jobs