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Original Investigation | August 29, 2016 FREE ONLINE FIRST

Effects of Cardiac Imaging vs Guideline-Directed Care on Unnecessary Angiography

This randomized trial compares the effects of care guided by cardiac MRI vs myocardial perfusion scintigraphy vs NICE guidelines on unnecessary angiography among patients with suspected coronary heart disease.

Featured article

Original Investigation | August 23, 2016 CME

Integrated Team-Based Care and Health Care Quality, Utilization, and Cost

This cohort study compares patient outcomes, health care utilization, and costs for patients receiving primary care in integrated team-based care vs traditional practice management practices.

Featured article

August 23, 2016

Host RNA Signatures for Distinguishing Bacterial From Viral Infections in Children

These studies describe development and diagnostic accuracy of host RNA biosignatures for distinguishing bacterial vs viral infection in young children.

Distinguishing Bacterial vs Viral Infection in Febrile Children
RNA Biosignatures and Bacterial Infections in Febrile Infants
Editorial: Genetics and the Evaluation of the Febrile Child


Featured article

Viewpoint | August 25, 2016 FREE ONLINE FIRST

Reassessing Cancer Compendia for Off-Label Oncology Prescribing

This Viewpoint discusses use of drug compendia for CMS approval of off-label drug use, compares recommendations between compendia, and proposes more contemporary standards for making coverage decisions.

Featured article

Viewpoint | August 22, 2016 FREE ONLINE FIRST

Lessons From the UK Junior Doctors’ Strike

This Viewpoint reviews the causes of the 2016 UK junior doctors’ strikes, residual issues preventing agreement between the NHS, junior doctors, and their union, and the potential long-term harm to UK medicine if an agreement is not reached.

Medical News & Perspectives

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Medical News & Perspectives | August 24, 2016 FREE ONLINE FIRST

Zika: Worse Than Thalidomide?

This Medical News feature compares and contrasts the known effects of Zika infection on the developing infant brain in utero to those of other congenital infections and teratogens.

Featured article

Medical News & Perspectives | August 19, 2016 FREE ONLINE FIRST

HIV/AIDS in 2016 and Beyond

This Medical News feature reviews progress in medical and public health responses to HIV/AIDS highlighted at the 21st International AIDS Conference in Durban, South Africa, in July 2016.

Clinical Review & Education

Featured article

Review | August 16, 2016 CME

Acute Aortic Dissection and Intramural Hematoma

This narrative review summarizes published evidence on diagnosis and management of acute aortic syndromes with a focus on the evolving roles of medical therapy vs TEVAR vs a traditional open surgical procedure.

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Author Interview

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Drug prices continue to rise in the US. Many solutions have been proposed but few have been implemented. Drs. Janet Woodcock from the FDA and Aaron Kesselheim, author of The High Cost of Prescription Drugs in the United States from the Harvard Medical School discuss the role of brand name drugs and generics and how they influence the cost of pharmaceuticals. Also see The Cost of US Pharmaceutical Price Reductions: A Financial Simulation Model of R&D Decisions by Thomas A. Abbott and John A. Vernon.

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The High Cost of Prescription Drugs in the United States Origins and Prospects for Reform

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JAMA Editor's Audio Summary

August 23, 2016

Distinguishing bacterial from viral infection in young children, team-based care and health care quality, managing prescription drug costs, and more

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Author Readings
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Reading by Graham McMahon, author of Advancing Continuing Medical Education

Latest Quiz

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Cutaneous Necrosis of the Ears

A 22-year-old woman presented with a 2-month history of fevers and pleuritic chest pain and a 2-day history of cutaneous necroses on her ears, without trauma. Evaluation revealed abnormal coagulation values and a deep vein thrombosis in one leg.

What would you do next?

From The JAMA Network

Time in Therapeutic Range in Warfarin-Treated Patients

JAMA Patient Page

For your patients: Planning to Return Home After Surgery.

Past JAMA Patient Pages are available in English and Spanish.

A Piece of My Mind


JAMA Medical Student Elective in Medical Editing

JAMA offers a 4-week elective in medical editing to third- and fourth-year US medical students. The elective is full-time and must be taken for academic credit. For information and an application, please email jamams@jamanetwork.org.

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Medical News

Threat From Colistin-Resistant Superbug

Visualizing Health Policy

HIV Awareness and Testing, 2013 AND 2014

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Physician Jobs