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IN THIS ISSUE

JAMA: The Journal of the American Medical Association

June 8, 2011, Vol 305, No. 22
Theme: Cancer
Basic View  |  Expanded View
Way Back When
Katherine E. Reeder-Hayes, MD, MBA
Topics:
JAMA. 2011;305(22):2266-2267.  doi: 10.1001/jama.2011.419
Effect of Screening on Ovarian Cancer Mortality: Title and subTitle BreakThe Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Randomized Controlled Trial FREE
Saundra S. Buys, MD; Edward Partridge, MD; Amanda Black, PhD, MPH; Christine C. Johnson, PhD, MPH; Lois Lamerato, PhD; Claudine Isaacs, MD; Douglas J. Reding, MD, MPH; Robert T. Greenlee, PhD, MPH; Lance A. Yokochi, MD, PhD; Bruce Kessel, MD; E. David Crawford, MD; Timothy R. Church, PhD, MS; Gerald L. Andriole, MD; Joel L. Weissfeld, MD, MPH; Mona N. Fouad, MD; David Chia, PhD; Barbara O’Brien, MPH; Lawrence R. Ragard, MD; Jonathan D. Clapp; Joshua M. Rathmell; Thomas L. Riley, BS; Patricia Hartge, ScD, MA; Paul F. Pinsky, PhD; Claire S. Zhu, PhD; Grant Izmirlian, PhD; Barnett S. Kramer, MD; Anthony B. Miller, MD; Jian-Lun Xu, PhD; Philip C. Prorok, PhD; John K. Gohagan, PhD; Christine D. Berg, MD; for the PLCO Project Team
Includes: Supplemental Content
Topics: lung, cancer, mortality, prostate, ovarian cancer, cancer screening
JAMA. 2011;305(22):2295-2303.  doi: 10.1001/jama.2011.766
Cancer Risks Associated With Germline Mutations in MLH1, MSH2, and MSH6 Genes in Lynch Syndrome FREE
Valérie Bonadona, MD, PhD; Bernard Bonaïti, MSc; Sylviane Olschwang, MD, PhD; Sophie Grandjouan, MD; Laetitia Huiart, MD; Michel Longy, MD, PhD; Rosine Guimbaud, MD; Bruno Buecher, MD, PhD; Yves-Jean Bignon, MD, PhD; Olivier Caron, MD; Chrystelle Colas, MD; Catherine Noguès, MD; Sophie Lejeune-Dumoulin, MD; Laurence Olivier-Faivre, MD, PhD; Florence Polycarpe-Osaer, MD; Tan Dat Nguyen, MD; Françoise Desseigne, MD; Jean-Christophe Saurin, MD, PhD; Pascaline Berthet, MD; Dominique Leroux, MD, PhD; Jacqueline Duffour, MD; Sylvie Manouvrier, MD, PhD; Thierry Frébourg, MD, PhD; Hagay Sobol, MD, PhD; Christine Lasset, MD, PhD; Catherine Bonaïti-Pellié, MD, PhD; for the French Cancer Genetics Network
Includes: Supplemental Content
Topics: mutation, cancer, colorectal cancer, hereditary nonpolyposis colorectal neoplasms, genes, germ-line mutation, neoplasms, cancer risk, msh2 gene, msh6 gene
JAMA. 2011;305(22):2304-2310.  doi: 10.1001/jama.2011.743
Long-term Risks of Subsequent Primary Neoplasms Among Survivors of Childhood Cancer FREE
Raoul C. Reulen, PhD; Clare Frobisher, PhD; David L. Winter; Julie Kelly; Emma R. Lancashire, PhD; Charles A. Stiller, MSc; Kathryn Pritchard-Jones, PhD, MD; Helen C. Jenkinson, PhD, MD; Michael M. Hawkins, DPhil; for the British Childhood Cancer Survivor Study Steering Group
Includes: Supplemental Content
Topics: survivors, neoplasms, childhood cancer
JAMA. 2011;305(22):2311-2319.  doi: 10.1001/jama.2011.747
Characteristics of Clinical Trials to Support Approval of Orphan vs Nonorphan Drugs for Cancer FREE
Aaron S. Kesselheim, MD, JD, MPH; Jessica A. Myers, PhD; Jerry Avorn, MD
Includes: Supplemental Content
Topics: antineoplastic agents, cancer, united states food and drug administration, surrogate endpoints
JAMA. 2011;305(22):2320-2326.  doi: 10.1001/jama.2011.769
KIT as a Therapeutic Target in Metastatic Melanoma FREE
Richard D. Carvajal, MD; Cristina R. Antonescu, MD; Jedd D. Wolchok, MD, PhD; Paul B. Chapman, MD; Ruth-Ann Roman, RN; Jerrold Teitcher, MD; Katherine S. Panageas, DrPH; Klaus J. Busam, MD; Bartosz Chmielowski, MD; Jose Lutzky, MD; Anna C. Pavlick, DO; Anne Fusco, MPA; Lauren Cane, BA; Naoko Takebe, MD; Swapna Vemula, MS; Nancy Bouvier, BS; Boris C. Bastian, MD, PhD; Gary K. Schwartz, MD
Includes: Supplemental Content
Topics: mutation, melanoma, mucous membrane, neoplasms, metastatic melanoma, imatinib mesylate, amplification
JAMA. 2011;305(22):2327-2334.  doi: 10.1001/jama.2011.746
Association Between Time to Initiation of Adjuvant Chemotherapy and Survival in Colorectal Cancer: Title and subTitle BreakA Systematic Review and Meta-analysis FREE
James J. Biagi, MD; Michael J. Raphael; William J. Mackillop, MB, ChB; Weidong Kong, MD, MSC; Will D. King, PhD; Christopher M. Booth, MD
Includes: CME , Supplemental Content
Topics: chemotherapy regimen, colorectal cancer, adjuvant chemotherapy
JAMA. 2011;305(22):2335-2342.  doi: 10.1001/jama.2011.749
A Strategic Approach to Therapeutic Cancer Vaccines in the 21st Century
Matthew M. Davis, MD, MAPP; Elias J. Dayoub, BA
Topics: cancer vaccines
JAMA. 2011;305(22):2343-2344.  doi: 10.1001/jama.2011.814
Balancing Access and Evaluation in the Approval of New Cancer Drugs
Franklin G. Miller, PhD; Steven Joffe, MD, MPH
Topics: antineoplastic agents
JAMA. 2011;305(22):2345-2346.  doi: 10.1001/jama.2011.784
Realigning Incentives for Developing and Pricing New Anticancer Treatments
David H. Howard, PhD
Topics: fees and charges, medicare, incentives
JAMA. 2011;305(22):2347-2348.  doi: 10.1001/jama.2011.793
Seeing the Future of Cancer-Associated Transcription Factor Drug Targets
Panagiotis A. Konstantinopoulos, MD, PhD; Athanasios G. Papavassiliou, MD, PhD
Topics: cancer, drug delivery systems, transcription factor
JAMA. 2011;305(22):2349-2350.  doi: 10.1001/jama.2011.727
Cancer Risk Assessment in Lynch Syndrome: Title and subTitle BreakDoes the Gene Matter?
Rosa M. Xicola, PhD; Xavier Llor, MD, PhD
Topics: hereditary nonpolyposis colorectal neoplasms, genes, cancer risk
JAMA. 2011;305(22):2351-2352.  doi: 10.1001/jama.2011.771
Axillary vs Sentinel Lymph Node Dissection for Invasive Breast Cancer
Seenu Vuthaluru, MS; Anurag Srivastava, MS, FRCS, MPhil, PhD
Topics:
JAMA. 2011;305(22):2288-2291.  doi: 10.1001/jama.2011.755
Axillary vs Sentinel Lymph Node Dissection for Invasive Breast Cancer
Benjamin O. Anderson, MD; Julie R. Gralow, MD
Topics:
JAMA. 2011;305(22):2288-2291.  doi: 10.1001/jama.2011.754
Axillary vs Sentinel Lymph Node Dissection for Invasive Breast Cancer
Merdan Fayda, MD; Ronald Chen, MD, MPH
Topics:
JAMA. 2011;305(22):2288-2291.  doi: 10.1001/jama.2011.753
Axillary vs Sentinel Lymph Node Dissection for Invasive Breast Cancer
Michael D. Hasselle, MD; Paige L. Dorn, MD
Topics:
JAMA. 2011;305(22):2288-2291.  doi: 10.1001/jama.2011.752
Axillary vs Sentinel Lymph Node Dissection for Invasive Breast Cancer
I-Chun Chen, MD; Ching-Hung Lin, MD; Yen-Shen Lu, MD, PhD
Topics:
JAMA. 2011;305(22):2288-2291.  doi: 10.1001/jama.2011.751
Axillary vs Sentinel Lymph Node Dissection for Invasive Breast Cancer
Ismail Jatoi, MD, PhD
Topics:
JAMA. 2011;305(22):2288-2291.  doi: 10.1001/jama.2011.750
Axillary vs Sentinel Lymph Node Dissection for Invasive Breast Cancer—Reply
Armando E. Giuliano, MD; Monica Morrow, MD; Karla V. Ballman, PhD
Topics:
JAMA. 2011;305(22):2288-2291.  doi: 10.1001/jama.2011.756
Bevacizumab and Cancer Treatment-Related Mortality
Patricia B. Cerrito, PhD
Topics:
JAMA. 2011;305(22):2291-2293.  doi: 10.1001/jama.2011.759
Bevacizumab and Cancer Treatment-Related Mortality
Cornelis J. A. Punt, MD, PhD; Linda Mol, MSc; Miriam Koopman, MD, PhD
Topics:
JAMA. 2011;305(22):2291-2293.  doi: 10.1001/jama.2011.758
Bevacizumab and Cancer Treatment-Related Mortality
Zu-Yao Yang, MD; Chen Mao, MD; Jin-Ling Tang, MD, PhD
Topics:
JAMA. 2011;305(22):2291-2293.  doi: 10.1001/jama.2011.757
Bevacizumab and Cancer Treatment-Related Mortality—Reply
Shenhong Wu, MD, PhD; Vishal Ranpura, MD; Sanjay Hapani, MD
Topics:
JAMA. 2011;305(22):2291-2293.  doi: 10.1001/jama.2011.760
Antibiotic Resistance and the Future
Kanika Deshpande Koirala, MBBS; Sudeep Dhoj Thapa, MBBS
Topics:
JAMA. 2011;305(22):2293-2294.  doi: 10.1001/jama.2011.761
Antibiotic Resistance and the Future—Reply
James M. Hughes, MD
Topics:
JAMA. 2011;305(22):2293-2294.  doi: 10.1001/jama.2011.762
Debate Continues on Use of PSA Testing for Early Detection of Prostate Cancer
M. J. Friedrich
Topics: prostate cancer, prostate-specific antigen screening, prostate cancer screening
JAMA. 2011;305(22):2273-2276.  doi: 10.1001/jama.2011.777
Retinoblastoma Therapy Delivers Power of Chemotherapy With Surgical Precision
M. J. Friedrich
Topics: chemotherapy regimen, retinoblastoma, surgical procedures, operative, precision
JAMA. 2011;305(22):2276-2278.  doi: 10.1001/jama.2011.778
Studies Probe Role of Telomere Length in Predicting, Modulating Cancer Risk
Tracy Hampton, PhD
Topics: cancer, telomere, cancer risk
JAMA. 2011;305(22):2278-2279.  doi: 10.1001/jama.2011.772
Cancer Survivors—United States, 2007 FREE
Topics: cancer, cancer survivorship
JAMA. 2011;305(22):2281-2282.  
Bullying Among Middle School and High School Students—Massachusetts, 2009 FREE
Topics: bullying
JAMA. 2011;305(22):2283-2286.  
Device Approval
Mike Mitka
Topics: device approval
JAMA. 2011;305(22):2280-2280.  doi: 10.1001/jama.2011.776
Measuring Countermeasures
Mike Mitka
Topics: anthrax disease, government, terrorism, vaccines, disasters and emergency preparedness, mass casualty setting, assault, devices, medical, health maintenance/preventive medicine
JAMA. 2011;305(22):2280-2280.  doi: 10.1001/jama.2011.774
Quality Improvement
Mike Mitka
Topics: quality improvement
JAMA. 2011;305(22):2280-2280.  doi: 10.1001/jama.2011.775
VA Oversight Questioned
Mike Mitka
Topics: hiv, fracture, dental equipment, ear, endoscopes, florida, government, pharynx, tennessee, united states department of veterans affairs, veterans, nose, viruses, safety culture, hepatitis exposure
JAMA. 2011;305(22):2280-2280.  doi: 10.1001/jama.2011.773
Penumbra
Thomas B. Cole, MD, MPH
Topics:
JAMA. 2011;305(22):2261-2261.  doi: 10.1001/jama.2011.770
For Harriet
Richard Schiffman
Topics:
JAMA. 2011;305(22):2263-2263.  doi: 10.1001/jama.2011.654
A Preliminary Report on the Mortality of Cancer in the United States, as Given by the Census of 1910
Topics:
JAMA. 2011;305(22):2359-2359.  doi: 10.1001/jama.2011.737
Adult Acute Lymphocytic Leukemia: Biology and Treatment
Paulette Mehta, MD, MPH
Topics:
JAMA. 2011;305(22):2353-2358.  doi: 10.1001/jama.2011.795
Cancer Genetics
Charis Eng, MD, PhD
Topics:
JAMA. 2011;305(22):2353-2358.  doi: 10.1001/jama.2011.794
From Dark Night to Gentle Surrender: On the Ethics and Spirituality of Hospice Care
Michael D. Barnett, MD
Topics:
JAMA. 2011;305(22):2353-2358.  doi: 10.1001/jama.2011.796
Hope in the Age of Anxiety
Elaine C. Meyer, PhD, RN
Topics:
JAMA. 2011;305(22):2353-2358.  doi: 10.1001/jama.2011.797
The Emperor of All Maladies: A Biography of Cancer
Paulette Mehta, MD, MPH
Topics:
JAMA. 2011;305(22):2353-2358.  doi: 10.1001/jama.2011.798
Error in Data Extraction and Analyses in: Treatment-Related Mortality With Bevacizumab in Cancer Patients: A Meta-analysis
Topics:
JAMA. 2011;305(22):2294-2294.  doi: 10.1001/jama.2011.763
Melanoma FREE
Ryszard M. Pluta, MD, PhD; Alison E. Burke, MA; Robert M. Golub, MD
Topics: melanoma
JAMA. 2011;305(22):2368-2368.  doi: 10.1001/jama.2011.658
About This Journal
Topics:
JAMA. 2011;305(22):2259-2260.  doi: 10.1001/jama.305.22.2259

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