TY  - JOUR
T1  - INtravesical bacille calmette-guérin in patients with asymptomatic bacteriuria
AU  - Herr HW
Y1  - 2011/04/13
N1  - 10.1001/jama.2011.428
JO  - JAMA
SP  - 1413
EP  - 1414
VL  - 305
IS  - 14
N2  - 
To the Editor: Asymptomatic bacteriuria is common in adults and does not require treatment.1 Practice guidelines, however, recommend antibiotics to sterilize the urine before urological procedures.2 Although intravesical bacille Calmette-Guérin (BCG) therapy for high-risk superficial bladder cancer is not specifically mentioned, urologists are reluctant to administer BCG to infected patients because of a possible risk of bacterial or BCG sepsis or an abrogated response to BCG.3 On the other hand, antibacterial treatment of asymptomatic bacteriuria leads to treatment delay and promotes antibiotic resistance. This study investigated whether intravesical BCG is safe and effective in bladder cancer patients with asymptomatic bacteriuria.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2011.428
UR  - http://dx.doi.org/10.1001/jama.2011.428
ER  -