TY  - JOUR
T1  - TReatment of chronic prostatitis/chronic pelvic pain syndrome
AU  - Jackson JL, Cohen JM, Dimitrakoff J
Y1  - 2011/04/06
N1  - 10.1001/jama.2011.399
JO  - JAMA
SP  - 1298
EP  - 1299
VL  - 305
IS  - 13
N2  - 
To the Editor: Although the direct meta-analysis methods that Dr Anothaisintawee and colleagues used in their review of the management of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)1 are mostly appropriate, we are concerned about the alternation between a random-effects and a fixed-effects model. In meta-analysis theory, when the heterogeneity of the studies is sufficiently low, the 2 models should produce the same result.2 However, if there is a significant difference between the results using fixed- and random-effects models, then a random-effects model should be used because it is more conservative. The tests for heterogeneity are notoriously insensitive.2

SN  - 0098-7484
M3  - doi: 10.1001/jama.2011.399
UR  - http://dx.doi.org/10.1001/jama.2011.399
ER  -