TY  - JOUR
T1  - SCientists find promising therapies for fragile x and down syndromes
AU  - Kuehn BM
Y1  - 2011/01/26
N1  - 10.1001/jama.2010.1960
JO  - JAMA
SP  - 344
EP  - 346
VL  - 305
IS  - 4
N2  - 
Advances in the understanding of the genetic and molecular basis of developmental disorders, as well as the creation of mouse models for these conditions, have led scientists studying them to some surprising insights. Even later in life, mice with Down syndrome or fragile X syndrome (FXS) that are given targeted treatment can experience improvements in cognitive function. Findings from such animal studies have paved the way to human trials to assess some of these potential therapies, with some experimental therapies for FXS already entering late-stage clinical trials.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2010.1960
UR  - http://dx.doi.org/10.1001/jama.2010.1960
ER  -