TY - JOUR T1 - SPontaneous gangrene in child, due to disease of vessel wall. Y1 - 1899/07/15 N1 - 10.1001/jama.1899.02450550054018 JO - Journal of the American Medical Association SP - 170 EP - 170 VL - XXXIII IS - 3 N2 - There have been a few instances described in which spontaneous gangrene has developed in rather young children; Reynaud has observed such cases. Leyden and others have described gangrene following typhoid fever and other infectious diseases. In a case described by Lehmann, symmetric gangrene, resembling senile gangrene, developed in a child 9 months old, apparently on account of changes in the vessel walls. Goebel1 describes the following case: For six weeks an eighteen months old child complained of pain in the left leg, which became blue, somewhat swollen, and cold to the touch. The clinical diagnosis was gangrene due to obstruction in the anterior tibial artery. At the autopsy there was found pneumonia, necrosis of the tonsils, and thrombosis of the abdominal aorta and the left popliteal and anterior tibial arteries; the thrombi were oldest in the popliteal artery. Where the popliteal artery branches, and in the first portion of the SN - 0002-9955 M3 - doi: 10.1001/jama.1899.02450550054018 UR - http://dx.doi.org/10.1001/jama.1899.02450550054018 ER -