TY  - JOUR
T1  - QUinin and urea hydrochlorid as a local anesthetic
AU  - HERTZLER AE, BREWSTER RB, ROGERS FB
Y1  - 1909/10/23
N1  - 10.1001/jama.1909.92550170048002a
JO  - Journal of the American Medical Association
SP  - 1393
EP  - 1395
VL  - LIII
IS  - 17
N2  - In September, 1907, Dr. Henry Thibault,1 of Scotts, Ark., published a short article calling attention to the local anesthetic effect of quinin and urea hydrochlorid. He recommended the use of a 1 per cent. solution for local injection and from 10 to 20 per cent. for local application to any mucous surfaces. Aside from this article by Dr. Thibault and one by E. J. Brown,2 recommending its use in tonsillectomy, we have been unable to find any account of the use of these substances for anesthetic purposes in the literature.For some six months we have been using this drug instead of cocain in all local anesthesias with the greatest satisfaction. So great has been the interest manifest in our studies by our professional friends that we have deemed it best to report our results up to date. Clinical experience was
SN  - 0002-9955
M3  - doi: 10.1001/jama.1909.92550170048002a
UR  - http://dx.doi.org/10.1001/jama.1909.92550170048002a
ER  -