TY - JOUR T1 - SErum sickness AU - Power H Y1 - 1909/05/08 N1 - 10.1001/jama.1909.02540450046013 JO - Journal of the American Medical Association SP - 1514 EP - 1515 VL - LII IS - 19 N2 - To the Editor:  —The increasing interest in serum poisoning, as shown by the recent report of cases, leads me to relate the following personal experience. I am furthermore induced to do so by the possibility herein shown of the sensitive condition far exceeding the usual time limits.In 1902, I attended a case of diphtheria. I took an immunizing injection of antitoxin of 1,000 units. No inconvenience or rash followed. A few months later my duties brought me into close relation with bubonic plague and I was injected with Haffkine's prophylactic. This is a vaccine. A very severe reaction followed, temperature rose to 102 F., there was much urticaria and general malaise for two days. I looked on this as a toxic and not a serum reaction. In January of this year I was in very close relation to an unusually severe case of diphtheria, in which I administered 108,000 SN - 0002-9955 M3 - doi: 10.1001/jama.1909.02540450046013 UR - http://dx.doi.org/10.1001/jama.1909.02540450046013 ER -