TY - JOUR T1 - APpendicostomy in pernicious anemia AU - BURCH LE Y1 - 1909/03/13 N1 - 10.1001/jama.1909.25420370046004g JO - Journal of the American Medical Association SP - 888 EP - 889 VL - LII IS - 11 N2 - Pernicious anemia is a primary anemia, characterized by a progressive diminution in the number and changes in the form of the red blood corpuscles associated with a decrease in the amount of hemoglobin, which is not so marked as the reduction in red blood cells. The disease usually terminates fatally, whatever the method of treatment, but often there are periods of marked improvement, followed by relapse. It is not within the province of this paper to discuss the etiology, pathology or symptoms of this disease; I shall limit myself instead to the treatment in those cases that are supposedly due to anaerobic bacteria in the intestinal tract. Herter, who is the pioneer in this line of work, asserts that anaerobic bacteria in the intestinal tract play a prominent part in the etiology of pernicious anemia. He has shown that oxygen is found only in the small intestine, and that for SN - 0002-9955 M3 - doi: 10.1001/jama.1909.25420370046004g UR - http://dx.doi.org/10.1001/jama.1909.25420370046004g ER -