TY  - JOUR
T1  - ANtibacterial or antitoxic immunization in tuberculin treatment
AU  - TRUDEAU EL
Y1  - 1909/01/23
N1  - 10.1001/jama.1909.25420300001001
JO  - Journal of the American Medical Association
SP  - 261
EP  - 263
VL  - LII
IS  - 4
N2  - Owing to the limitations of our knowledge as to the effect of tuberculin on the tuberculous organism and to a most indefinite conception of its action, the best method to be followed in its therapeutic application still remains unsettled and to a great degree empirical. Leaving aside the minor debatable details of the treatment, two most important features in its application still remain unsettled; namely, the part played by moderate reactions and the place held in our conception of the treatment by tuberculin immunization. Are moderate reactions beneficial or always injurious? Is the highest limit of tolerance, attainable through steady progression in dosage, the object to be held in view in applying the treatment? These questions can not be definitely settled until we have a clearer conception of just what we are trying to accomplish by tuberculin injections than we have at present.Two very widely differing conceptions of what
SN  - 0002-9955
M3  - doi: 10.1001/jama.1909.25420300001001
UR  - http://dx.doi.org/10.1001/jama.1909.25420300001001
ER  -