TY - JOUR T1 - RAynaud's disease and scleroderma AU - Horwitz O Y1 - 1979/04/27 N1 - 10.1001/jama.1979.03290430018015 JO - JAMA SP - 1794 EP - 1794 VL - 241 IS - 17 N2 - To the Editor.—  I should like to take Orville Horwitz, MD, of Philadelphia, to task on one point that he made concerning Raynaud's disease in answering a question for The Journal (184:85, 1963). I had occasion to read his response lately and was horrified to note the following: "Raynaud's disease itself is a nuisance rather than a serious condition and endangers neither life nor limb. It is, however, frequently a prelude to scleroderma (50% to 90% of the time, depending on whose series)."I feel certain that today's response would be: "Raynaud's disease is on rare occasions a prelude to scleroderma, but in the great majority of cases it is a mere transient phenomenon."Almost any general practitioner would have told this to Horwitz. The trouble was that most of the literature on Raynaud's disease at that time was written by academic surgeons who saw almost exclusively the most severe SN - 0098-7484 M3 - doi: 10.1001/jama.1979.03290430018015 UR - http://dx.doi.org/10.1001/jama.1979.03290430018015 ER -