TY  - JOUR
T1  - ACcessory spleen in hodgkin's disease
AU  - Strauch GO
Y1  - 1979/04/27
N1  - 10.1001/jama.1979.03290430016012
JO  - JAMA
SP  - 1792
EP  - 1793
VL  - 241
IS  - 17
N2  - To the Editor.— 
    The problem of dealing with accessory spleens in patients undergoing laparotomy for abdominal staging of Hodgkin's disease, addressed by Jacobson and Reynolds (240:2081, 1978), seems worthy of further comment in view of two recent developments.The first of these is the growing realization that the problem of postsplenectomy sepsis in patients with Hodgkin's disease who have undergone total splenic ablation is of such magnitude that reappraisal of the value of total splenectomy for some patients seems in order. An assessment of the literature published since the risk of postsplenectomy sepsis in these patients became manifest indicates that the risk may range from about 10% overall1 to more than 20% in patients who require aggressive multimodal therapy for their disease.2 Since the mortality of patients with postsplenectomy sepsis remains extremely high, regardless of therapy once sepsis occurs, and since measures for prevention of postsplenectomy sepsis have
SN  - 0098-7484
M3  - doi: 10.1001/jama.1979.03290430016012
UR  - http://dx.doi.org/10.1001/jama.1979.03290430016012
ER  -