TY  - JOUR
T1  - IRreversible renal failure following vesicoureteral reflux
AU  - Senekjian HO, Stinebaugh BJ, Mattioli CA, Suki WN
Y1  - 1979/01/12
N1  - 10.1001/jama.1979.03290280040025
JO  - JAMA
SP  - 160
EP  - 162
VL  - 241
IS  - 2
N2  - Antireflux surgery was performed in five patients with vesicoureteral reflux at a time when renal insufficiency was present. Notable proteinuria was present in four of the patients, and a kidney biopsy specimen showed glomerular lesions in one. Despite the eradication of reflux and of infection, all five patients continued to have progressive renal insufficiency culminating in renal failure. Vesicoureteral reflux nephropathy may include a glomerulopathy leading to progressive glomerular sclerosis. Antireflux surgery would not alter this ongoing process and therefore would not halt progressive renal failure.(JAMA 241:160-162, 1979)
SN  - 0098-7484
M3  - doi: 10.1001/jama.1979.03290280040025
UR  - http://dx.doi.org/10.1001/jama.1979.03290280040025
ER  -