TY - JOUR T1 - IMprovement of rheumatoid arthritis following splenectomy for felty syndrome AU - Khan MA, Kushner I Y1 - 1977/03/14 N1 - 10.1001/jama.1977.03270380060021 JO - JAMA SP - 1116 EP - 1118 VL - 237 IS - 11 N2 - A patient with Felty syndrome underwent splenectomy because of persistent high fever, leg ulcer, and granulocytopenia. Subsequently, his rheumatoid synovitis went into prolonged remission. In addition, the leg ulcer healed; his WBC count, hemoglobin level, temperature, ESR, and weight returned to normal; the rheumatoid factor titer dropped substantially; and the antinuclear antibodies disappeared. These changes have persisted to the present time, more than 5 1/2 years after surgery.(JAMA 237:1116-1118, 1977) SN - 0098-7484 M3 - doi: 10.1001/jama.1977.03270380060021 UR - http://dx.doi.org/10.1001/jama.1977.03270380060021 ER -