TY  - JOUR
T1  - ABnormal insulin in myocardial infarction
Y1  - 1969/12/08
N1  - 10.1001/jama.1969.03160360061017
JO  - JAMA
SP  - 1915
EP  - 1916
VL  - 210
IS  - 10
N2  - Despite the fact that good, statistically acceptable investigations (Howell and Wilson1 and Paul et al2) have refuted Yudkin's hypothesis, which maintains that high sugar intake is the chief dietary factor in the etiology of coronary heart disease, it is clear that a clinical association does exist between faulty carbohydrate metabolism, abnormal lipid pattern, and myocardial infarction. Chance, Albutt, and Edkins3 demonstrated that total serum lipid was elevated in 64% of patients and serum cholesterol in 43% of a series of untreated diabetic children; abnormal lipoprotein patterns were found in 77% of all juvenile diabetics tested. In another study4 the same authors discovered that a normal lipid pattern could be sustained over a period of ten years in properly treated juvenile diabetics on a standard diabetic diet; those on an unsaturated fatty-acid-rich diet did not fare any better. This implies that other, nondietary factors may be involved
SN  - 0098-7484
M3  - doi: 10.1001/jama.1969.03160360061017
UR  - http://dx.doi.org/10.1001/jama.1969.03160360061017
ER  -