TY  - JOUR
T1  - REcurrent hepatitis and halothane
AU  - Mohler DN
Y1  - 1969/11/03
N1  - 10.1001/jama.1969.03160310096032
JO  - JAMA
SP  - 908
EP  - 908
VL  - 210
IS  - 5
N2  - To the Editor:— 
    In The Journal (209:946, 1969) a question from a physician in Illinois concerns a patient with recurrent attacks of hepatitis. The answer raised the possibility, among others, of multiple viral exposures.Another possibility occurred to me which would merit looking into. Is it possible that this patient has been having recurrent exposures to halothane at his place of work? It is mentioned in the case description that he is a hospital employee. A strikingly similar case was described by Klatskin and Kimberg (New Eng J Med280:515, 1969). An anesthesiologist who had recurrent attacks of hepatitis which were found to be caused by exposure to halothane and cleared completely when he avoided halothane exposure. The recurrent hepatitis described in The Journal question is consistent with recurrent exposure to a hepatotoxin, and it would be of great interest and possible therapeutic importance to determine whether the
SN  - 0098-7484
M3  - doi: 10.1001/jama.1969.03160310096032
UR  - http://dx.doi.org/10.1001/jama.1969.03160310096032
ER  -