TY  - JOUR
T1  - SErum enzyme values in infectious mononucleosis
AU  - Black MB
Y1  - 1969/10/20
N1  - 10.1001/jama.1969.03160290111042
JO  - JAMA
SP  - 559
EP  - 559
VL  - 210
IS  - 3
N2  - To the Editor:— 
    The dissociation of serum bilirubin concentration and alkaline phosphatase activity described by Shuster and Ognibene (209:267, 1969) has also been noted in this laboratory. Additional information has been obtained with serum transaminase values and lactic dehydrogenase (LDH) levels with isoenzymes.In acute infectious mononucleosis without icterus, the LDH level is consistently elevated (700 to 1400 units) and the alkaline phosphatase activity may rise to 10 Bodansky units. Despite significant hyperbilirubinemia in infectious mononucleosis, the transaminase values are both consistently below 200 units, the alkaline phosphatase activity below 20 units, and the lethal dose (LD5) liver fraction is less than 20%. In infectious hepatitis, the LD5 is more than 50% in almost all cases and the transaminase values numerically approximate the LDH values.
SN  - 0098-7484
M3  - doi: 10.1001/jama.1969.03160290111042
UR  - http://dx.doi.org/10.1001/jama.1969.03160290111042
ER  -