TY  - JOUR
T1  - CAsting light on dim
Y1  - 1969/10/06
N1  - 10.1001/jama.1969.03160270088019
JO  - JAMA
SP  - 126
EP  - 127
VL  - 210
IS  - 1
N2  - Hemodialysis and renal transplantation have provided many fringe benefits. In addition to prolonging life of the individual patient, they have enriched medical science with a better understanding of metabolic disorders in chronic renal failure as well as with a clearer appreciation of the kidney's role in blood formation, in blood volume and blood pressure regulation, and in immunogenesis. Not the least of these gains has been the opportunity which prolongation of life, with or without benefit of functioning kidney tissue, has presented for the study of renal handling of divalent ion metabolism (DIM) in chronic kidney failure. And the striking increase in skeletal complications from 25% to 80% consequent to hemodialysis and renal transplantation has added therapeutic challenge to the scientific quest for concepts and mechanisms.Renal osteodystrophy and metastatic calcification of soft tissue complicating disordered DIM in kidney failure are intimately interwoven with widely scattered metabolic disorders of calcium
SN  - 0098-7484
M3  - doi: 10.1001/jama.1969.03160270088019
UR  - http://dx.doi.org/10.1001/jama.1969.03160270088019
ER  -