TY  - JOUR
T1  - THe colloidal gold test of the spinal fluid
AU  - Green JB
Y1  - 1969/09/22
N1  - 10.1001/jama.1969.03160250064028
JO  - JAMA
SP  - 1908
EP  - 1908
VL  - 209
IS  - 12
N2  - To the Editor:— 
    Nicholas J. Fiumara, MD (Question and Answers, 208:2168, 1969), stated in reply to a question about Lange's colloidal gold test, that it "offers little more in diagnostic help than the total protein test [of cerebrospinal fluid]."This statement may be valid in respect to the diagnosis of neurosyphilis but is incorrect if applied to neurologic diagnosis in general.1 Multiple sclerosis and subacute sclerosing panencephalitis are two diseases often associated with an abnormal gold curve in the presence of a normal cerebrospinal fluid total protein value. In fact, an abnormal gold curve may call attention to these diagnostic possibilities, when they have not been previously suspected. In such cases a sample of cerebrospinal fluid should be sent to a more specialized laboratory which can perform electrophoretic studies.
SN  - 0098-7484
M3  - doi: 10.1001/jama.1969.03160250064028
UR  - http://dx.doi.org/10.1001/jama.1969.03160250064028
ER  -