TY - JOUR T1 - A guide to the problem of photosensitivity AU - Kalivas J Y1 - 1969/09/15 N1 - 10.1001/jama.1969.03160240062018 JO - JAMA SP - 1706 EP - 1709 VL - 209 IS - 11 N2 - Cutaneous eruptions more or less confined to light-exposed areas are not uncommon. Despite numerous exhaustive reviews1-7 published in recent years, it is difficult for most practitioners to acquire a real diagnostic expertise in this field. Too often, the only characteristic feature in any given case is the distribution of the lesions. Hopefully, the following schemes will provide some new perspectives and helpful insights by plotting differentiating features as attributes against the primary light-sensitive dermatoses; by commenting on the more important (or more interesting) photosensitizing drugs and contactants; and, finally, by indicating which laboratory tests are likely to be of specific diagnostic value when the history and physical findings are inconclusive (as, for example, in protoporphyria).I. The physical examination and historyB. Extrinsic photosensitivity1. Internal agents* (drug-induced)Sulfonamides†—uncommon with modern analogues, in contrast to the older drug, sulfanilamideSulfonylureas†Thiazides,† quinethazone†—may have only pruritus in sun-exposed sites SN - 0098-7484 M3 - doi: 10.1001/jama.1969.03160240062018 UR - http://dx.doi.org/10.1001/jama.1969.03160240062018 ER -