TY - JOUR T1 - PSychopharmacology AU - Friedman S Y1 - 1969/07/28 N1 - 10.1001/jama.1969.03160170061031 JO - JAMA SP - 565 EP - 565 VL - 209 IS - 4 N2 - In a scant 15 years psychopharmacology has come of age; this book confers upon it the mantle of maturity. A welcome relief from psychiatric cant and theory, it summarizes in magnificent scope our scientific knowledge of drugs currently available in psychiatric therapeutics. In some 450 double-columned pages, the history, chemical composition, physiological-pharmacological action, and clinical investigation of every pertinent drug have been superbly reviewed.In certain areas the experience of individual investigators may differ somewhat from some opinions expressed in this extensive presentation. For example, I have not found that the desmethylated compounds of imipramine or amitriptyline act more rapidly than their parent drugs. Nor have I been able definitely to correlate the ultimate response to the antidepressant drugs with their therapeutic action during the first week of administration, since their effect during that early period is usually quite negligible. My experience negates the use of these compounds in personality SN - 0098-7484 M3 - doi: 10.1001/jama.1969.03160170061031 UR - http://dx.doi.org/10.1001/jama.1969.03160170061031 ER -