TY - JOUR T1 - ENdocarditis from serratia marcescens AU - Quintiliani R, Gifford RH Y1 - 1969/06/16 N1 - 10.1001/jama.1969.03160110027006 JO - JAMA SP - 2055 EP - 2059 VL - 208 IS - 11 N2 - Despite the increasing frequency of nosocomial infections due to nonpigmented strains of Serratia marcescens, infective endocarditis from this organism is rare. This communication adds three such cases to the previously reported four. Five of the seven patients succumbed to infection. Some predisposing factor could be identified in all seven. Therapy was extremely difficult because of resistance to antibiotics and persistence of infection despite the use of appropriate chemotherapeutic agents, including nalidixic acid intravenously, used unsuccessfully in two patients. The difficulty in eradicating this infection once it has become established on a prosthetic valve is evident. The possibility that intravenous foreign bodies are a source of infection must be considered. SN - 0098-7484 M3 - doi: 10.1001/jama.1969.03160110027006 UR - http://dx.doi.org/10.1001/jama.1969.03160110027006 ER -