TY  - JOUR
T1  - TOpical administration of vitamin a acid for ichthyosiform dermatoses and psoriasis
AU  - Frost P, Weinstein GD
Y1  - 1969/03/10
N1  - 10.1001/jama.1969.03150230077007
JO  - JAMA
SP  - 1863
EP  - 1868
VL  - 207
IS  - 10
N2  - Therapeutic responses to topical administration of preparations containing 0.1% to 0.3% vitamin A acid and control bases applied to contralateral areas of involvement were compared in 26 patients with psoriasis, 8 with ichthyosis vulgaris, 8 with X-linked ichthyosis, 17 with lamellar ichthyosis, and 10 with epidermolytic hyperkeratosis. Topical administration of vitamin A acid was most effective in psoriasis, lamellar ichthyosis, and epidermolytic hyperkeratosis, disorders associated with epidermal cell hyperplasia; it did not appear to be effective in ichthyosis vulgaris. Irritation with higher concentrations of vitamin A acid, which subsided rapidly when the medication was withheld, was the only adverse effect noted.
SN  - 0098-7484
M3  - doi: 10.1001/jama.1969.03150230077007
UR  - http://dx.doi.org/10.1001/jama.1969.03150230077007
ER  -