TY - JOUR T1 - MEdical news Y1 - 1969/02/17 N1 - 10.1001/jama.1969.03150200033003 JO - JAMA SP - 1267 EP - 1284 VL - 207 IS - 7 N2 - Hemophilia Treated With Spleen Cells  Spleen cell infusions have been used to treat severe hemophilia in six patients. The results are promising, according to California investigators."There was a reduction in bleeding episodes and demonstrable rises in factors VIII and IX," says R.G. Desai, MD. He is chief of hematology at Orange County Medical Center, and assistant professor of medicine, University of California at Irvine.The increased levels of factors VIII and IX have persisted for periods up to nine months—the longest follow-up at the time Dr. Desai and his co-workers reported their results to the Western Section meeting of the American Federation for Clinical Research.Of the patients, four had factor VIII deficiency (hemophilia A), one had factor IX deficiency (hemophilia B), and one had Von Willebrand's disease.All but the patient with Von Willebrand's disease had pretreatment levels of factor VIII or IX of less than 1% SN - 0098-7484 M3 - doi: 10.1001/jama.1969.03150200033003 UR - http://dx.doi.org/10.1001/jama.1969.03150200033003 ER -