TY - JOUR T1 - GAs in the intestinal wall AU - Seaman WB Y1 - 1969/01/06 N1 - 10.1001/jama.1969.03150140103029 JO - JAMA SP - 151 EP - 151 VL - 207 IS - 1 N2 - To the Editor:—  In regard to two recent reports of pneumatosis intestinalis in patients with scleroderma that were submitted by Meihoff et al (204:854, 1968) and Atlas (205: 939, 1968), I would like to point out that gas within the wall of the bowel may be seen in a variety of conditions characterized by intestinal distention and/or ulcerative disease. The latter is not essential and it is probable that the mucosal ischemia associated with distention for long periods may result in varying degrees of mucosal necrosis, which also permits gas to enter the wall of the gut. Rigler and Pogue (Amer J Roentgen94:402, 1965) pointed out the high frequency of intramural gas with mucosal necrosis and indeed pointed out that intramural gas was a fairly reliable sign of mucosal necrosis.The first case of intramural gas within the small-bowel wall occurring in patient with scleroderma was reported by SN - 0098-7484 M3 - doi: 10.1001/jama.1969.03150140103029 UR - http://dx.doi.org/10.1001/jama.1969.03150140103029 ER -