TY  - JOUR
T1  - TReatment of shoulder-hand syndrome with griseofulvin
AU  - Cohen A, Goldman J, Daniels R, Kanenson W
Y1  - 1960/06/04
N1  - 10.1001/jama.1960.73020230041009
JO  - Journal of the American Medical Association
SP  - 542
EP  - 543
VL  - 173
IS  - 5
N2  - When griseofulvin (Fulvicin) was made available for the treatment of fungus diseases, there was some question whether it was fungistatic or fungicidal. This became evident when fungus infections of the finger or toe nails were treated.1 The growth was apparently inhibited by continuous treatment for a number of months, while an old nail was replaced by a new one. If treatment was discontinued before the new nail had completely appeared, the fungus would start growing again and the prior condition would return.Since inflammation accompanying some fungus diseases of the skin1 subsides rather abruptly, it was thought possible by us that griseofulvin might be another anti-inflammatory agent. Proceeding on this assumption, we decided to administer the drug to some of our patients with rheumatoid arthritis. Among the group of patients were a few with cases of shoulder-hand syndrome. The response in patients with rheumatoid arthritis was negative, while
SN  - 0002-9955
M3  - doi: 10.1001/jama.1960.73020230041009
UR  - http://dx.doi.org/10.1001/jama.1960.73020230041009
ER  -