TY  - JOUR
T1  - "Constitutional" allergic reactions and their prevention
AU  - Waldbott GL
Y1  - 1959/10/31
N1  - 10.1001/jama.1959.03010270008002
JO  - Journal of the American Medical Association
SP  - 1172
EP  - 1176
VL  - 171
IS  - 9
N2  - The major occasions for constitutional allergic reactions are intradermal tests with allergens, treatments with antigens, sclerosing injections for varicose veins, local anesthetics, injections of radiopaque mediums for roentgenographic diagnosis, injections of antibiotics and hormones, inhalation of airborne substances, and ingestion of foods or drugs to which the patient is sensitive. Treatment of reactions must be prompt. Epinephrine and a tourniquet are the first standbys. Intradermal tests should be done only on arms and legs where a tourniquet can be applied and not on the back. Penicillin should never be given without a preliminary intradermal test and should not be injected into the hips or trunk where a tourniquet cannot be applied. The danger is lessened by proper timing of injections and by preliminary injection of a small test dose of a drug before the full intended dose is given.
SN  - 0002-9955
M3  - doi: 10.1001/jama.1959.03010270008002
UR  - http://dx.doi.org/10.1001/jama.1959.03010270008002
ER  -