TY - JOUR T1 - POstmortem diagnosis of insulin shock AU - Naumann HN Y1 - 1959/01/24 N1 - 10.1001/jama.1959.03000210102017 JO - Journal of the American Medical Association SP - 408 EP - 408 VL - 169 IS - 4 N2 - To the Editor:—  In the article by Birkinshaw and co-workers (Investigations in a Case of Murder by Insulin Poisoning, Brit. M. J.2:463-468 [Aug. 23] 1958) discussed in the Foreign Letters section of The Journal (168:811 [Oct. 11] 1958) detection, identification, and quantitation of insulin were ingeniously achieved in tissue extracts from sites of needle marks in the victim's buttocks. However, in spite of large amounts of insulin in the body of the victim, paradoxically, not hypoglycemia but a hyperglycemia of 210 mg. per 100 ml. was demonstrated about six hours after death. Postmortem chemistry, so far, has been applied mainly as aid in autopsy diagnosis of diabetes mellitus (Hamilton-Patterson and Johnson, J. Path. & Bact. 50:473-482 [May] 1940; Tonge and Wannan, M. J. Australia1:439-447 [April 2] 1949; and Naumann, Am. J. Clin. Path. 20:314-324 [April] 1950) but rarely of insulin shock. Proof of SN - 0002-9955 M3 - doi: 10.1001/jama.1959.03000210102017 UR - http://dx.doi.org/10.1001/jama.1959.03000210102017 ER -