TY - JOUR T1 - CUrrent comment Y1 - 1949/08/13 N1 - 10.1001/jama.1949.02900500028012 JO - Journal of the American Medical Association SP - 1220 EP - 1220 VL - 140 IS - 15 N2 - NODULAR PANNICULITIS—WEBER-CHRISTIAN DISEASE  Weber-Christian's disease, or nonsuppurative nodular panniculitis, is characterized by recurring episodes of fever and the development of numerous painful and slightly tender subcutaneous nodules. In only 3 of 33 recorded cases was death apparently due to the disease. In the case reported by Kritzler,1 in which necropsy was done, the nodular lesions were limited to the subcutaneous fat. However, fat emboli were found in the lungs and there was widespread acute necrosis of the liver and spleen. In the case examined at necropsy by Spain and Foley,2 necrotic areas were found not only in the subcutaneous fat but in the mesenteric, omental and pretracheal fat. Fat emboli were not found in the lungs, nor were areas of necrosis observed in the liver or spleen. However, foci of fat necrosis were present in the region of the pancreas. A third case investigated at necropsy was that SN - 0002-9955 M3 - doi: 10.1001/jama.1949.02900500028012 UR - http://dx.doi.org/10.1001/jama.1949.02900500028012 ER -